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Limitin Protein, Mouse, Recombinant (His)

(Synonyms: Lmtn, Limitin, interferon ζ, interferon zeta, IFN-ζ, IFN-zeta, IFN-z, Ifnz, BGIF) Copy Product Info

Synonyms: Lmtn, Limitin, interferon ζ, interferon zeta, IFN-ζ, IFN-zeta, IFN-z, Ifnz, BGIF

Catalog No. TMPJ-01371 Copy Product Info
Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of MHC class I expression, and the growth inhibition of a myelomonocytic leukemia cell line.
Limitin Protein, Mouse, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$11235 days35 days
10 μg$18335 days35 days
20 μg$29235 days35 days
50 μg$54535 days35 days
100 μg$81335 days35 days
200 μg$1,19035 days35 days
500 μg$2,07035 days35 days
1 mg$2,97035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of MHC class I expression, and the growth inhibition of a myelomonocytic leukemia cell line.
Species
Mouse
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberQ9R1T0
Amino AcidLeu22-Arg182
ConstructionLeu22-Arg182
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsLmtn, Limitin, interferon ζ, interferon zeta, IFN-ζ, IFN-zeta, IFN-z, Ifnz, BGIF
Research Background
Chemical Properties
Molecular Weight19 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Limitin Protein, Mouse, Recombinant (His) chemical structure | Limitin Protein, Mouse, Recombinant (His) molecular weight