Imidaprilate

Name: Imidaprilate
Brand: TargetMol
SKU: T11642
Rating: 4.5 (1 reviews)

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Catalog No. T11642Cas No. 89371-44-8

Alias Imidaprilat, 6366A

Imidaprilate, an active metabolite of TA-6366, is a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM) used in hypertension research.

Imidaprilate

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Catalog No. T11642Alias Imidaprilat, 6366ACas No. 89371-44-8

Imidaprilate, an active metabolite of TA-6366, is a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM) used in hypertension research.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 μg	$398	35 days	35 days
1 mg	$715	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Product Introduction

Bioactivity

Description	Imidaprilate, an active metabolite of TA-6366, is a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM) used in hypertension research.
Targets&IC50	ACE:2.6 nM
In vitro	Imidaprilate augments the bradykinin-induced contraction of guinea pig ileum, with AC50 of 1.7 nM.Imidaprilate ?is an active metabolite of 6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM.
In vivo	Imidaprilate (≥0.2 mg/kg) inhibits the pressor response induced by angiotensin I (AT-I).
Synonyms	Imidaprilat, 6366A

Chemical Properties

Molecular Weight	377.39
Formula	C₁₈H₂₃N₃O₆
Cas No.	89371-44-8
Relative Density.	1.356 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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