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D-Pantothenic acid

Name: D-Pantothenic acid
Brand: TargetMol
SKU: T6480
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: vitamin B5, pantothenate) Copy Product Info

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Synonyms: vitamin B5, pantothenate

Catalog No. T6480 Copy Product Info

Purity: 99.92%

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D-Pantothenic acid (vitamin B5) is an essential micronutrient and a precursor to coenzyme A. D-Pantothenic acid participates in the metabolism of the three major nutrients—fat, carbohydrates, and protein—within the body. D-Pantothenic acid also plays a crucial role in skin barrier repair, maintaining hematopoietic function, and synthesizing adrenal hormones.

Cas No. 79-83-4

Pack Size	Price	USA Stock	Global Stock
100 mg	$35	In Stock	In Stock
500 mg	$56	-	In Stock
1 g	$78	-	In Stock
5 g	$163	-	In Stock
1 mL x 10 mM (in DMSO)	$40	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.92%

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	D-Pantothenic acid (vitamin B5) is an essential micronutrient and a precursor to coenzyme A. D-Pantothenic acid participates in the metabolism of the three major nutrients—fat, carbohydrates, and protein—within the body. D-Pantothenic acid also plays a crucial role in skin barrier repair, maintaining hematopoietic function, and synthesizing adrenal hormones.
In vivo	Methods: ICR pregnant mice (8.5 days gestation) were administered valproic acid (VPA: 300, 400, 500 mg/kg) via subcutaneous injection and D-Pantothenic acid (PTA: 3×10, 3×100, 3×300 mg/kg) via intraperitoneal injection; In the combination group, PTA was administered 1 hour before, immediately upon, and 1 hour after VPA administration; embryonic development and malformations were assessed at 18.5 days of gestation. Results: D-Pantothenic acid reduced valproic acid-induced neural tube defects in mice. [1]
Synonyms	vitamin B5, pantothenate

Chemical Properties

Molecular Weight	219.24
Formula	C₉H₁₇NO₅
Cas No.	79-83-4
Smiles	CC(C)(CO)[C@@H](O)C(=O)NCCC(O)=O
Relative Density.	1.266 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 255 mg/mL (1163.11 mM), Sonication is recommended.

H2O: 50 mg/mL (228.06 mM)

In Vivo Formulation

10% DMSO+90% Saline: 1 mg/mL (4.56 mM), Solution.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5612 mL	22.8061 mL	45.6121 mL	228.0606 mL
5 mM	0.9122 mL	4.5612 mL	9.1224 mL	45.6121 mL
10 mM	0.4561 mL	2.2806 mL	4.5612 mL	22.8061 mL
20 mM	0.2281 mL	1.1403 mL	2.2806 mL	11.4030 mL
50 mM	0.0912 mL	0.4561 mL	0.9122 mL	4.5612 mL
100 mM	0.0456 mL	0.2281 mL	0.4561 mL	2.2806 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.