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Anti-gp130/IL6ST Antibody (7J799) (Synonyms: interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130)

Name: Anti-gp130/IL6ST Antibody (7J799)
Brand: TargetMol
SKU: TMAY-03136
Rating: 4.5 (1 reviews)

Catalog No. TMAY-03136 Copy Product Info

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Anti-gp130/IL6ST Antibody (7J799) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (7J799) can be used in FCM.

Anti-gp130/IL6ST Antibody (7J799)

Copy Product Info

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Catalog No. TMAY-03136

Synonyms interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130

Anti-gp130/IL6ST Antibody (7J799) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (7J799) can be used in FCM.

Anti-gp130/IL6ST Antibody
(7J799)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$268	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-gp130/IL6ST Antibody (7J799) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (7J799) can be used in FCM.
Synonyms	interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130
Ig Type	Rabbit IgG
Clone	7J799
Reactivity	Mouse
Specificity	Mouse gp130/IL6ST
Verified Activity	Flow cytometric analysis of Mouse IL6ST(CD130) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse IL6ST(CD130), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application	FCM
Recommended Dose	FCM: 1:25-1:100
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL6ST/gp130/CD130 (rM IL6ST/gp130/CD130; TMPY-01832; NP_034690.3; Met1-Glu617).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively, spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1, and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events.

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	APC/PE
Antibody Types Available	3

Antigen Details

Immunogen	Recombinant Protein: Mouse IL6ST/gp130/CD130 Protein (TMPY-01832)
Antigen Species	Mouse

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

GP-130GP 130CDW-130CDW 130CD-130CD 130

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