Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-TIMP-1 Antibody (7V648)

😃Good
Catalog No. TMAY-01347
Alias TIMP metallopeptidase inhibitor 1

Anti-TIMP-1 Antibody (7V648) is a Mouse antibody targeting TIMP-1. Anti-TIMP-1 Antibody (7V648) can be used in ELISA.

Anti-TIMP-1 Antibody (7V648)

Anti-TIMP-1 Antibody (7V648)

😃Good
Catalog No. TMAY-01347Alias TIMP metallopeptidase inhibitor 1
Anti-TIMP-1 Antibody (7V648) is a Mouse antibody targeting TIMP-1. Anti-TIMP-1 Antibody (7V648) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$198 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-TIMP-1 Antibody (7V648) is a Mouse antibody targeting TIMP-1. Anti-TIMP-1 Antibody (7V648) can be used in ELISA.
AliasTIMP metallopeptidase inhibitor 1
Ig Type
Monoclonal Mouse IgG1
Clone
7V648
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TIMP1 (rhTIMP1; TMPY-00932; NP_003245.1; Met 1-Ala 207). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Human cell-derived TIMP1 protein (TMPY-00932)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-TIMP-1 Antibody (7V648) | purchase Anti-TIMP-1 Antibody (7V648) | Anti-TIMP-1 Antibody (7V648) cost | order Anti-TIMP-1 Antibody (7V648)