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Anti-CD40 Antibody-PE (1W671)
🥰Excellent
Catalog No. TMAY-03759P
Anti-CD40 Antibody-PE (1W671) is a PE-conjugated Mouse antibody targeting CD40. Anti-CD40 Antibody-PE (1W671) can be used in FCM.
Anti-CD40 Antibody-PE (1W671)
Anti-CD40 Antibody-PE (1W671)
🥰Excellent
Catalog No. TMAY-03759P
Anti-CD40 Antibody-PE (1W671) is a PE-conjugated Mouse antibody targeting CD40. Anti-CD40 Antibody-PE (1W671) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD40 Antibody-PE (1W671) is a PE-conjugated Mouse antibody targeting CD40. Anti-CD40 Antibody-PE (1W671) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 1W671 |
| Reactivity | Rat |
| Verified Activity | Flow cytometric analysis of Rat CD40 expression on rat splenocytes. SD splenocytes were stained with PE-conjugated anti-Rat CD40 and FITC conjugated anti-Rat CD3 (BD Pharmingen™ Cat. No. 557354). The dot plots were derived from events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD40 / TNFRSF5 (rR CD40 / TNFRSF5; TMPY-03203; NP_599187.1; Met1-Arg193) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Rat CD40 / TNFRSF5 protein (TMPY-03203) |
| Antigen Species | Rat |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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