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2'-NH2-ATP

Catalog No. T40696 CAS 61468-88-0

Synonyms: 2'-NH2-ATP, 2'-Amino-2'-deoxyadenosine-5'-triphosphate

2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling.

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2'-NH2-ATP, CAS 61468-88-0

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Description	2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling.
In vitro	2'-NH2-ATP (2 mM) was ineffective as a substitute for ATP in the NH3-dependent formation of cytidine 5'-triphosphate (CTP) mediated by CTP synthase[2].

Synonyms	2'-NH2-ATP, 2'-Amino-2'-deoxyadenosine-5'-triphosphate
Molecular Weight	506.197
Formula	C10H17N6O12P3
CAS No.	61468-88-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Armstrong VW, et, al. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem. 1976 Nov 1;70(1):33-8. 2. Faylene A. L. KINETIC STUDIES ON WILD-TYPE AND MUTANT ESCHERICHIA COLICYTIDINE 5'-TRIPHOSPHATE SYNTHASES AND INHIBITOR DEVELOPMENT. Dalhousie University Halifax, Nova Scotia. 2008 Jul. 3. Aström H, et, al. Acidity of secondary hydroxyls in ATP and adenosine analogues and the question of a 2',3'-hydrogen bond in ribonucleosides. J Am Chem Soc. 2004 Nov 17;126(45):14710-1.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

2'-NH2-ATP 61468-88-0 2'NH2ATP 2' NH2 ATP 2'-Amino-2'-deoxyadenosine-5'-triphosphate 2'-NH-2-ATP inhibitor inhibit

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