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Anti-NXPH1 Antibody (2E440) is a Rabbit antibody targeting NXPH1. Anti-NXPH1 Antibody (2E440) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-NXPH1 Antibody (2E440) is a Rabbit antibody targeting NXPH1. Anti-NXPH1 Antibody (2E440) can be used in IHC-P. |
Alias | neurexophilin 1, C130005L03Rik |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2E440 |
Reactivity | Rat |
Verified Activity | 1. Immunochemical staining of rat NXPH1 in rat spinal cord with rabbit monoclonal antibody (1:20000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of rat NXPH1 in rat brain with rabbit monoclonal antibody (1:20000, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:10000-1:20000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat Neurexophilin-1 / NXPH1 (rR Neurexophilin-1 / NXPH1; TMPY-02058; Q63366-1; Met1-Gly271). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Neurexophilin-1 or NXPH1 is a secreted glycoprotein, which belongs to the Neurexophilin family. The Neurexophilin family contains at least four genes and resembles a neuropeptide, suggesting a function as an endogenous ligand for alpha-neurexins. The mammalian brains contain four genes for neurexophilins the products of which share a common structure composed of five domains: an N-terminal signal peptide, a variable N-terminal domain, a highly conserved central domain that is N-glycosylated, a short linker region, and a conserved C-terminal domain that is cysteine-rich. Neurexophilin-1 constitutes a secreted cysteine-rich glycoprotein, forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. Neurexophilins 1 and 3 but not 4 (neurexophilin 2 is not expressed in rodents) bind to a single individual LNS domain, the second overall LNS domain in all three alpha-neurexins. |
Conjucates | Unconjugated |
Immunogen | Recombinant Rat Neurexophilin-1 / NXPH1 protein (TMPY-02058) |
Antigen Species | Rat |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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