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Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) is a rat inhibitory antibody that specifically targets mouse CD25/IL-2Rα. It can deplete CD25-positive T cells and is suitable for immunology and inflammation-related research, including atopic dermatitis.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $98 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $355 | 2-4 weeks | 2-4 weeks | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
| Description | Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) is a rat inhibitory antibody that specifically targets mouse CD25/IL-2Rα. It can deplete CD25-positive T cells and is suitable for immunology and inflammation-related research, including atopic dermatitis. |
| In vivo | Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) administered intraperitoneally at 400 μg three times weekly for 3 consecutive weeks depletes CD25‑positive T cells in a mouse model of immune thrombocytopenia [1]. In a mouse model of atopic dermatitis, intraperitoneal injection of 300 μg of Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) every 2 days starting 2 days before MC904 treatment effectively relieves atopic dermatitis symptoms in mice [2]. |
| Clone | PC-61.5.3 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD25/IL-2Rα |
| Molecular Weight | 150 kDa |
| Storage | Store at -20°C Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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