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Anti-NGAL/Lipocalin-2 Antibody (6S836)
🥰Excellent
Catalog No. TMAY-03736
Anti-NGAL/Lipocalin-2 Antibody (6S836) is a Rabbit antibody targeting NGAL/Lipocalin-2. Anti-NGAL/Lipocalin-2 Antibody (6S836) can be used in ELISA.
Anti-NGAL/Lipocalin-2 Antibody (6S836)
Anti-NGAL/Lipocalin-2 Antibody (6S836)
🥰Excellent
Catalog No. TMAY-03736
Anti-NGAL/Lipocalin-2 Antibody (6S836) is a Rabbit antibody targeting NGAL/Lipocalin-2. Anti-NGAL/Lipocalin-2 Antibody (6S836) can be used in ELISA.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-NGAL/Lipocalin-2 Antibody (6S836) is a Rabbit antibody targeting NGAL/Lipocalin-2. Anti-NGAL/Lipocalin-2 Antibody (6S836) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6S836 |
| Reactivity | Rat |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat NGAL/LCN2/Lipocalin-2 (rR NGAL/LCN2/Lipocalin-2; TMPY-02316; P30152; Met1-Asn198). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells, like kidney tubular cells, may produce NGAL in response to various insults. This protein is released from injured tubular cells after various damaging stimuli, is already known by nephrologists as one of the most promising biomarkers of incoming Acute Kidney Injury (AKI). Recent evidence also suggests its role as a biomarker in a variety of other renal and non-renal conditions. Moreover, recent studies seem to suggest a potential involvement of this factor also in the genesis and progression of chronic kidney diseases. NGAL is the first known mammalian protein that specifically binds organic molecules called siderophores, which are high-affinity iron chelators. NGAL, first known as an antibacterial factor of natural immunity, and an acute-phase protein, is currently one of the most interesting and enigmatic proteins involved in the process of tumor development. acting as an intracellular iron carrier and protecting MMP9 from proteolytic degradation, NGAL has a clear pro-tumoral effect, as has already been observed in different tumors (e.g. breast, stomach, esophagus, brain) in humans. In thyroid carcinomas, NGAL is strongly induced by NF-kB, an important factor involved both in tumor growth and in the link between chronic inflammation and neoplastic development. Thus, Lipocalin-2 (LCN2/NGAL) has been implicated in a variety of processes including cell differentiation, proliferation, survival, and morphogenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Rat NGAL/LCN2/Lipocalin-2 Protein (TMPY-02316) |
| Antigen Species | Rat |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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