Your shopping cart is currently empty

DSPE-PEG-Maleimide (MW 5000) is a functionalized phospholipid derivative commonly used in the construction of liposomes and nanoparticles. Its terminal maleimide group allows for stable chemical conjugation with thiol-containing biomolecules.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $44 | - | In Stock | |
| 25 mg | $86 | - | In Stock | |
| 50 mg | Preferential | - | In Stock |
| Description | DSPE-PEG-Maleimide (MW 5000) is a functionalized phospholipid derivative commonly used in the construction of liposomes and nanoparticles. Its terminal maleimide group allows for stable chemical conjugation with thiol-containing biomolecules. |
| Targets&IC50 | VEGF:< 1 nM(Kd) |
| In vitro | DSPE-PEG-Maleimide (MW 5000) functions as a reactive linker for conjugating thiolated ligands like p53 peptides [1]. It also enables the covalent attachment of thiolated monoclonal antibodies (e.g., OX26-SH) to liposomes to create targeted immunoliposomes [2]. |
| In vivo | Liposomes containing 3% DSPE-PEG-Maleimide (MW 5000) demonstrate high physical stability with a constant diameter of 120 nm over two weeks [3]. This stability ensures reliable drug delivery and consistent pharmacokinetics in brain targeting models [2][3]. |
| Molecular Weight | 5000 (Average) |
| Smiles | CCCCCCCCCCCCCCCCCC(O[C@](COP(OCCNC(COCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)([O-])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O)=O.[MW 5000].[Na+].[n] |
| Relative Density. | no data available |
| Storage | store at low temperature | In solvent: -80°C for 1 year |
| Solubility Information | DMSO: 40.00 mg/mL, Sonication is recommended. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
| Size | Quantity | Unit Price | Amount | Operation |
|---|

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.