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HIF-1 alpha (556-574) TFA (1201633-99-9 free base)

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Catalog No. TP1546
Alias HIF-1 alpha (556-574) TFA

This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process.

HIF-1 alpha (556-574) TFA (1201633-99-9 free base)
Other Forms of HIF-1 alpha (556-574) TFA (1201633-99-9 free base):
HIF-1 alpha (556-574)TP15331201633-99-9
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HIF-1 alpha (556-574) TFA (1201633-99-9 free base)

😃Good
Catalog No. TP1546Alias HIF-1 alpha (556-574) TFA
This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process.
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Product Introduction

Bioactivity
Description
This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process.
SynonymsHIF-1 alpha (556-574) TFA
Chemical Properties
Molecular Weight2368.62
FormulaC103H151D2F3N20O36S2
Relative Density.no data available
SequenceH-Asp-Leu-Asp-Leu-Glu-Met-Leu-Ala-Pro-Tyr-Ile-Pro-Met-Asp-Asp-Asp-Phe-Gln-Leu-OH
Sequence ShortDLDLEMLAPYIPMDDDFQL
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: Soluble

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

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