PVRIG Protein, Mouse, Recombinant (hFc & Avi)

Name: PVRIG Protein, Mouse, Recombinant (hFc & Avi)
Brand: TargetMol
SKU: TMPK-00470
Rating: 4.5 (1 reviews)

(Synonyms: RMO1, RalGDS/AF-6, PVRIG, PREL-2, PREL2, MGC2463, MGC138297, MGC104322, LPD, CD112R, C7orf15, ALS2CR9, ALS2CR18) Copy Product Info

Synonyms: RMO1, RalGDS/AF-6, PVRIG, PREL-2, PREL2, MGC2463, MGC138297, MGC104322, LPD, CD112R, C7orf15, ALS2CR9, ALS2CR18

Catalog No. TMPK-00470 Copy Product Info

Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.70 kDa and the accession number is A0A1B0GS01.

PVRIG Protein, Mouse, Recombinant (hFc & Avi)

Pack Size	Price	USA Stock	Global Stock
5 µg	$58	7-10 days	7-10 days
10 µg	$92	7-10 days	7-10 days
20 µg	$148	7-10 days	7-10 days
50 µg	$289	7-10 days	7-10 days
100 µg	$487	7-10 days	7-10 days
200 µg	$883	7-10 days	7-10 days
500 µg	$1,950	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Mouse Nectin-2, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Mouse PVRIG, hFc Tag with the EC50 of 0.81ug/ml determined by ELISA.
Description	Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.70 kDa and the accession number is A0A1B0GS01.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc-Avi
Accession Number	A0A1B0GS01
Construction	Ser35-Asp165
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	RMO1, RalGDS/AF-6, PVRIG, PREL-2, PREL2, MGC2463, MGC138297, MGC104322, LPD, CD112R, C7orf15, ALS2CR9, ALS2CR18
Research Background	Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.

Chemical Properties

Molecular Weight

42.70 kDa (predicted). Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.