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Anti-GOLPH2/GOLM1 Antibody (3K657) is a Mouse antibody targeting GOLPH2/GOLM1. Anti-GOLPH2/GOLM1 Antibody (3K657) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-GOLPH2/GOLM1 Antibody (3K657) is a Mouse antibody targeting GOLPH2/GOLM1. Anti-GOLPH2/GOLM1 Antibody (3K657) can be used in IHC-P. |
Alias | PSEC0257, HEL46, GP73, GOLPH2, golgi membrane protein 1, C9orf155, bA379P1.3 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 3K657 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human GOLM1 in human liver with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to cytoplasm of hepatocyte and interlobular bile duct. 2. Immunochemical staining of human GOLM1 in human endometrium with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to cytoplasm of uterine gland. |
Application | IHC-P |
Recommended Dose | IHC-P: 1:50-1:200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GOLM1 / GP73 (rh GOLM1 / GP73; TMPY-02193; Q8NBJ4-1; Val 40-Leu 401). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncytial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human GOLM1 / GP73 protein (TMPY-02193) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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