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CT-1 Protein, Human, Recombinant (His)

(Synonyms: CTF1, CT-1, Cardiotrophin-1) Copy Product Info

Synonyms: CTF1, CT-1, Cardiotrophin-1

Catalog No. TMPJ-00086 Copy Product Info
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$11235 days35 days
10 μg$18335 days35 days
20 μg$29235 days35 days
50 μg$54535 days35 days
100 μg$81335 days35 days
200 μg$1,19035 days35 days
500 μg$2,07035 days35 days
1 mg$2,97035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.
Species
Human
Expression System
E. coli
TagN-6xHis
Accession NumberQ16619
Amino AcidMet1-Ala201
ConstructionMet1-Ala201
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of PBS, 2 mM EDTA, 5% Trehalose, pH 7.4.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsCTF1, CT-1, Cardiotrophin-1
Research Background
Chemical Properties
Molecular Weight25 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: CT-1 Protein, Human, Recombinant (His) chemical structure | CT-1 Protein, Human, Recombinant (His) molecular weight