Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Skp2 inhibitor 2 (14f) impedes the F-box protein S-phase kinase-associated protein 2 (Skp2), demonstrating an IC50 of 10.2 μM against Skp2-Cks1. This compound targets Skp2, a component of cullin-RING ligases that recruits and ubiquitinates substrates, playing roles in both proteolytic and non-proteolytic processes [1].
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Description | Skp2 inhibitor 2 (14f) impedes the F-box protein S-phase kinase-associated protein 2 (Skp2), demonstrating an IC50 of 10.2 μM against Skp2-Cks1. This compound targets Skp2, a component of cullin-RING ligases that recruits and ubiquitinates substrates, playing roles in both proteolytic and non-proteolytic processes [1]. |
Molecular Weight | 428.57 |
Formula | C27H32N4O |
CAS No. | 2760612-77-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Skp2 inhibitor 2 2760612-77-7 Ubiquitination E1/E2/E3 Enzyme inhibitor inhibit