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Anti-PRP19 Antibody (7U313)
😃Good
Catalog No. TMAC-03446
Alias UBOX4, SNEV, Senescence evasion factor, psoralen 4, PSO4, PRPF19, PRP19_HUMAN, PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae), PRP19/PSO4 homolog, PRP 19, Pre-mRNA-processing factor 19, pre mRNA processing factor 19, Nuclear matrix protein NMP200 related to splicing factor PRP19, Nuclear matrix protein 200, NMP200, hPso4
Anti-PRP19 Antibody (7U313) is a Rabbit antibody targeting PRP19. Anti-PRP19 Antibody (7U313) can be used in FCM,ICC,IHC,WB.
Anti-PRP19 Antibody (7U313)
Anti-PRP19 Antibody (7U313)
😃Good
Catalog No. TMAC-03446Alias UBOX4, SNEV, Senescence evasion factor, psoralen 4, PSO4, PRPF19, PRP19_HUMAN, PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae), PRP19/PSO4 homolog, PRP 19, Pre-mRNA-processing factor 19, pre mRNA processing factor 19, Nuclear matrix protein NMP200 related to splicing factor PRP19, Nuclear matrix protein 200, NMP200, hPso4
Anti-PRP19 Antibody (7U313) is a Rabbit antibody targeting PRP19. Anti-PRP19 Antibody (7U313) can be used in FCM,ICC,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PRP19 Antibody (7U313) is a Rabbit antibody targeting PRP19. Anti-PRP19 Antibody (7U313) can be used in FCM,ICC,IHC,WB. |
| Synonyms | UBOX4, SNEV, Senescence evasion factor, psoralen 4, PSO4, PRPF19, PRP19_HUMAN, PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae), PRP19/PSO4 homolog, PRP 19, Pre-mRNA-processing factor 19, pre mRNA processing factor 19, Nuclear matrix protein NMP200 related to splicing factor PRP19, Nuclear matrix protein 200, NMP200, hPso4 |
| Ig Type | IgG |
| Clone | 7U313 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PRP19 on Jurkat cells lysates using anti-PRP19 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-PRP19 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-PRP19 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PRP19 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PRP19 antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-PRP19 antibody. Counter stained with hematoxylin. 7. ICC staining PRP19 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. ICC staining PRP19 in B16-F1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 9. ICC staining PRP19 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 10. Flow cytometric analysis of Hela cells with PRP19 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.           |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The spliceosome, the 0gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and five RNA molecules (U1, U2, U4, U5 and U6). Pre-mRNA splicing is essential to remove internal non-coding regions of pre-mRNA (introns) and to join the remaining segments (exons) into mRNA before translation. The PRP19-associated complex is required for stable association of U5 and U6 with the spliceosome after U4 is released. Changes within the spliceosome upon binding of the PRP19-associated complex include remodeling of the U6/5' splice site interaction and destabilization of Lsm proteins to allow further interaction of U6 with the intron sequence. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 55 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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