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Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)

(Synonyms: Snaclec rhodocytin subunit alpha, Rhodoaggretin subunit alpha, Aggretin alpha chain) Copy Product Info

Synonyms: Snaclec rhodocytin subunit alpha, Rhodoaggretin subunit alpha, Aggretin alpha chain

Catalog No. TMPH-00320 Copy Product Info
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 17.8 kDa and the accession number is Q9I841.
Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$14320 days20 days
10 μg$23820 days20 days
20 μg$39720 days20 days
50 μg$59720 days20 days
100 μg$84520 days20 days
200 μg$1,19020 days20 days
500 μg$1,95020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 90% as determined by SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 17.8 kDa and the accession number is Q9I841.
Species
Calloselasma rhodostoma
Expression System
P. pastoris (Yeast)
TagN-6xHis
Accession NumberQ9I841
Amino AcidGLEDCDFGWSPYDQHCYQAFNEQKTWDEAEKFCRAQENGAHLASIESNGEADFVSWLISQKDELADEDYVWIGLRAQNKEQQCSSEWSDGSSVSYENLIDLHTKKCGALEKLTGFRKWVNYYCEQMHAFVCKLLPY
Construction1-136 aa
Protein Purity
> 90% as determined by SDS-PAGE.
https://cdn.targetmol.com/group3/M00/3F/D8/CgoaEGh2NMWEIWNZAAAAABQUyf0968.jpg
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsSnaclec rhodocytin subunit alpha, Rhodoaggretin subunit alpha, Aggretin alpha chain
Research Background
Chemical Properties
Molecular Weight17.8 kDa (predicted)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His) chemical structure | Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His) molecular weight