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Acesulfame Potassium

Name: Acesulfame Potassium
Brand: TargetMol
SKU: T0940
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0940Cas No. 55589-62-3

Acesulfame potassium is a non-nutritive sweetener.

Acesulfame Potassium

🥰Excellent

Purity: 99.65%

Catalog No. T0940Cas No. 55589-62-3

Acesulfame potassium is a non-nutritive sweetener.

Pack Size	Price	USA Warehouse	Global Warehouse
2 g	$36	-	In Stock
5 g	$56	-	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.65%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	Acesulfame potassium is a non-nutritive sweetener.
In vitro	In male Wistar rats, Acesulfame potassium (150 mg/kg) has been shown to induce insulin secretion.
In vivo	In cells expressing hTAS2R44 (EC50=2.5 mM), Acesulfame potassium induces a significant increase in intracellular solute calcium (Ca 2+) levels.

Chemical Properties

Molecular Weight	201.24
Formula	C₄H₄KNO₄S
Cas No.	55589-62-3
Smiles	[K+].CC1=CC(=O)[N-]S(=O)(=O)O1
Relative Density.	>= 1.856 - <= 1.856 g/cm³. Temperature:20.4 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 37 mg/mL (183.86 mM), Sonication is recommended.

DMSO: 55 mg/mL (273.31 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.94 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.9692 mL	24.8460 mL	49.6919 mL	248.4596 mL
5 mM	0.9938 mL	4.9692 mL	9.9384 mL	49.6919 mL
10 mM	0.4969 mL	2.4846 mL	4.9692 mL	24.8460 mL
20 mM	0.2485 mL	1.2423 mL	2.4846 mL	12.4230 mL
50 mM	0.0994 mL	0.4969 mL	0.9938 mL	4.9692 mL
100 mM	0.0497 mL	0.2485 mL	0.4969 mL	2.4846 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc