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Anti-MSX2 Polyclonal Antibody is a Rabbit antibody targeting MSX2. Anti-MSX2 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-MSX2 Polyclonal Antibody is a Rabbit antibody targeting MSX2. Anti-MSX2 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | PFM1, PFM 1, PFM, Parietal foramina 1, Msx2/Hox8, MSX2, Msx 2, Msh homeobox homolog 2, Msh homeobox 2, Msh homeo box homolog 2, Msh homeo box homolog, Msh homeo box 2, MSH, Hox8, Hox 8, Homeobox protein MSX-2, Homeobox protein MSX2, Homeobox protein Hox-8, Homeo box msh like 2, FPP, CRS2, CRS 2 |
| Ig Type | IgG |
| Reactivity | (predicted:Human,Mouse,Rat,Chicken,Dog,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human Msx2/Hox8 |
| Antigen Species | Human |
| Gene Name | MSX2 |
| Gene ID | |
| Protein Name | Homeobox protein MSX-2 |
| Uniprot ID | |
| Biology Area | Signal transduction,Transcription factors/regulators,Other factors,Neurogenesis |
| Function | Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter. |
| Molecular Weight | Theoretical: 29 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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