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PSB-1491

Name: PSB-1491
Brand: TargetMol
SKU: T24680
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T24680Cas No. 1619884-67-1

PSB-1491 is a selective and competitive monoamine oxidase B inhibitor with an IC50 of 0.386 nM, demonstrating over 25,000-fold selectivity compared to MAO-A.

PSB-1491

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Purity: 99.68%

Catalog No. T24680Cas No. 1619884-67-1

PSB-1491 is a selective and competitive monoamine oxidase B inhibitor with an IC50 of 0.386 nM, demonstrating over 25,000-fold selectivity compared to MAO-A.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$108	In Stock	In Stock
10 mg	$162	In Stock	In Stock
25 mg	$268	In Stock	In Stock
50 mg	$392	In Stock	In Stock
100 mg	$668	In Stock	In Stock
500 mg	$2,530	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.68%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	PSB-1491 is a selective and competitive monoamine oxidase B inhibitor with an IC50 of 0.386 nM, demonstrating over 25,000-fold selectivity compared to MAO-A.
Targets&IC50	MAO-B:0.386 nM(human)

Chemical Properties

Molecular Weight	320.17
Formula	C₁₅H₁₁Cl₂N₃O
Cas No.	1619884-67-1
Smiles	CN1C=2C(=CC(C(NC3=CC(Cl)=C(Cl)C=C3)=O)=CC2)C=N1
Relative Density.	1.43 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (156.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1233 mL	15.6167 mL	31.2334 mL	156.1670 mL
5 mM	0.6247 mL	3.1233 mL	6.2467 mL	31.2334 mL
10 mM	0.3123 mL	1.5617 mL	3.1233 mL	15.6167 mL
20 mM	0.1562 mL	0.7808 mL	1.5617 mL	7.8084 mL
50 mM	0.0625 mL	0.3123 mL	0.6247 mL	3.1233 mL
100 mM	0.0312 mL	0.1562 mL	0.3123 mL	1.5617 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc