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Anti-Phospho-AURKB (Thr232) Polyclonal Antibody (Synonyms: p-AURKB (Thr232), p-AURKB (T232), AURKB (p-Thr232)|...)

Catalog No. TMAC-00347 Copy Product Info
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Anti-Phospho-AURKB (Thr232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AURKB (Thr232). Anti-Phospho-AURKB (Thr232) Polyclonal Antibody can be used in WB.

Anti-Phospho-AURKB (Thr232) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00347
Synonyms p-AURKB (Thr232), p-AURKB (T232), AURKB (p-Thr232), AURKB (p-T232)

Anti-Phospho-AURKB (Thr232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AURKB (Thr232). Anti-Phospho-AURKB (Thr232) Polyclonal Antibody can be used in WB.

Anti-Phospho-AURKB
(Thr232) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-AURKB (Thr232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AURKB (Thr232). Anti-Phospho-AURKB (Thr232) Polyclonal Antibody can be used in WB.
Synonymsp-AURKB (Thr232), p-AURKB (T232), AURKB (p-Thr232), AURKB (p-T232)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from COS7 cells treated with Nocodazole using Phospho-AurB (Thr232) antibody TMAC-00347. The lane on the right is treated with the antigen-specific peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundSerine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 232 (R-K-T(p)-M-C) derived from Human AurB
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 39 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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