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Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) is a Mouse antibody targeting Phospho-PTK2 (Ser 722). Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) can be used in WB,IP,IF,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) is a Mouse antibody targeting Phospho-PTK2 (Ser 722). Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) can be used in WB,IP,IF,IHC-P. |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Activation of integrins in the extracellular matrix (ECM) of eukaryotic cells promotes the formation of membrane adhesion complexes, known as focal adhesions, which can include cytoskeletal proteins and protein tyrosine kinases, such as focal adhesion kinase (FAK). Phosphorylation events occurring within focal adhesions influence numerous processes that include mitogenic signaling, cell survival and cell motility. FAK is a non-receptor tyrosine kinase that is ubiquitously expressed and highly conserved between species. FAK is recruited by integrin clusters and variably phosphorylated depending on the effector molecules present in the focal adhesion. Phospho-rylation of FAK Tyr 397 decreases during serum starvation, contact inhibition and cell cycle arrest, all conditions under which activating FAK Tyr 407 phosphorylation increases. |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | Peptide |
Antigen Species | Peptide |
Uniprot ID |
Molecular Weight | Theoretical: 125 kDa. |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
Transport | Shipping with blue ice. |
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