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4-carboxy TEMPO

Name: 4-carboxy TEMPO
Brand: TargetMol
SKU: T35948
Rating: 4.5 (1 reviews)

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Catalog No. T35948Cas No. 37149-18-1

4-carboxy TEMPO is a nitroxide and spin label. Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo., It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.

4-carboxy TEMPO

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Catalog No. T35948Cas No. 37149-18-1

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$113	35 days	35 days
100 mg	$217	35 days	35 days
250 mg	$297	35 days	35 days
500 mg	$493	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	200.26
Formula	C₁₀H₁₈NO₃
Cas No.	37149-18-1
Smiles	CC1(C)CC(CC(C)(C)N1O)C(O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 30 mg/mL (149.81 mM), Sonication is recommended.

Ethanol: 30 mg/mL (149.81 mM), Sonication is recommended.

DMSO: 30 mg/mL (149.81 mM), Sonication is recommended.

PBS (pH 7.2): 10 mg/mL (49.94 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.9935 mL	24.9675 mL	49.9351 mL	249.6754 mL
5 mM	0.9987 mL	4.9935 mL	9.9870 mL	49.9351 mL
10 mM	0.4994 mL	2.4968 mL	4.9935 mL	24.9675 mL
20 mM	0.2497 mL	1.2484 mL	2.4968 mL	12.4838 mL

DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0999 mL	0.4994 mL	0.9987 mL	4.9935 mL
100 mM	0.0499 mL	0.2497 mL	0.4994 mL	2.4968 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

4-carboxy TEMPO4carboxy TEMPO4 carboxy TEMPO