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Synonyms: zcyto18, TIFIL-23, TIFa, interleukin 22, IL-TIF, ILTIF, IL-D110, IL-22, IL22, IL-21


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $148 | 7-10 days | 7-10 days | |
| 10 µg | $247 | 7-10 days | 7-10 days | |
| 20 µg | $385 | 7-10 days | 7-10 days | |
| 50 µg | $697 | 7-10 days | 7-10 days | |
| 100 µg | $1,130 | 7-10 days | 7-10 days | |
| 200 µg | $1,860 | 7-10 days | 7-10 days | |
| 500 µg | $3,580 | 7-10 days | 7-10 days | |
| 1 mg | $5,880 | 7-10 days | 7-10 days |
| Bioactivity | ED 50 < 0.5 ng/ml, measured by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells). |
| Description | IL-22 Protein, Mouse, Recombinant (CHO) is expressed in CHO Cells. The accession number is Q9JJY9. |
| Species | Mouse |
| Expression System | CHO Cells |
| Tag | Tag Free |
| Accession Number | Q9JJY9 |
| Construction | Leu34-Val179 |
| Protein Purity | > 95% as determined by SDS-PAGE; > 95% as determined by HPLC |
| Endotoxin | < 0.2 EU/μg of protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | zcyto18, TIFIL-23, TIFa, interleukin 22, IL-TIF, ILTIF, IL-D110, IL-22, IL22, IL-21 |
| Research Background | Interleukin-22 (IL-22) is a member of a group of cytokines called the IL-10 family which include IL-10,IL-19, IL-20, IL-24, and IL-26. IL-22 shares use of the IL-10R2 in cell signaling with other members of this family IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. IL-22 is produced by activated DCs and T cells and initiates an innate immune response against bacterial pathogens especially in epithelial cells such as those in the respiratory tract and gut. IL-22 along with IL-17 is rapidly produced by splenic LTi-like cells and can also be produced by Th17 cells, which plays a likely role in the coordinated response of both adaptive and innate immune systems. |
| Molecular Weight | 20~30 kDa (Reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
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