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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Cbz-NH-PEG8-CH2COOH is a PEG-based linker for PROTACs that connects two essential ligands, crucial for forming PROTAC molecules, and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins, utilizing two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the protein of interest [1]. |
Molecular Weight | 561.62 |
Formula | C26H43NO12 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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