Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppressive and antiinflammatory properties.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 44.00 | |
50 μg | 5 days | $ 190.00 | |
500 μg | 5 days | $ 834.00 | |
1 mg | 5 days | $ 1,400.00 |
Description | Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppressive and antiinflammatory properties. |
Species | Human |
Expression System | E. coli |
Tag | C-6His |
Accession Number | P09382 |
Synonyms | HPL, S-Lac Lectin 1, Lactose-Binding Lectin 1, 14 kDa Lectin, Beta-Galactoside-Binding Lectin L-14-I, Gal-1, HBL, Lectin Galactoside-Binding Soluble 1, Galectin-1, Putative MAPK-Activating Protein PM12, Galaptin, LG, HLBP14, 14 kDa Laminin-Binding Protein, β-Galactoside-Binding Lectin L-14-I |
Amino Acid | Ala2-Asp135 |
Construction | Recombinant Human Galectin-1 is produced by our E.coli expression system and the target gene encoding Ala2-Asp135 is expressed with a 6His tag at the C-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 15 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Citrate, 8% Trehalose, 4% Mannitol, 50mM NaCl, 1mM TCEP, 0.05% Tween 80, pH 4.0. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppressive and antiinflammatory properties. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
LGALS1 Protein, Human, Recombinant (His) HLBP-14 HPL S-Lac Lectin 1 Lactose-Binding Lectin 1 14 kDa Lectin Beta-Galactoside-Binding Lectin L-14-I Gal-1 HBL Lectin Galactoside-Binding Soluble 1 Galectin-1 HLBP 14 Putative MAPK-Activating Protein PM12 Galaptin LG HLBP14 14 kDa Laminin-Binding Protein b-Galactoside-Binding Lectin L-14-I β-Galactoside-Binding Lectin L-14-I recombinant recombinant-proteins proteins protein