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Neuropeptide Y Y1 receptor antagonist 1

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Catalog No. T74350Cas No. 2773476-40-5

Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, acts as a potent antagonist against the neuropeptide Y Y1 receptor (Y1R) with a Kᵢ value of 0.19 nM [1]. It should be stored in conditions shielded from light.

Neuropeptide Y Y1 receptor antagonist 1

Neuropeptide Y Y1 receptor antagonist 1

😃Good
Catalog No. T74350Cas No. 2773476-40-5
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, acts as a potent antagonist against the neuropeptide Y Y1 receptor (Y1R) with a Kᵢ value of 0.19 nM [1]. It should be stored in conditions shielded from light.
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Product Introduction

Bioactivity
Description
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, acts as a potent antagonist against the neuropeptide Y Y1 receptor (Y1R) with a Kᵢ value of 0.19 nM [1]. It should be stored in conditions shielded from light.
Targets&IC50
NPYY1 receptor:.19 nM (Ki)
Chemical Properties
Molecular Weight1115.28
FormulaC62H70N10O10
Cas No.2773476-40-5
SmilesC([O-])(=O)C1=C(C=2C3=C([O+]=C4C2C=CC(N(C)C)=C4)C=C(N(C)C)C=C3)C=CC(C(NCCCCOC5=CC([C@@H](C(N[C@@H](C(NCC6=CC=C(O)C=C6)=O)CCCNC(NC(NCCNC(CC)=O)=O)=N)=O)C7=CC=CC=C7)=CC=C5)=O)=C1
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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