Powder: -20°C for 3 years | In solvent: -80°C for 1 year
USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM). USP15-IN-1 showed high antiproliferative activity against non-small cell lung cancer and leukemia cells. USP15 is an interacting protein of cGAS, and USP15 can promote cGAS to recognize DNA and activate downstream signaling pathways.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 128.00 | |
5 mg | In stock | $ 322.00 | |
10 mg | In stock | $ 511.00 | |
25 mg | In stock | $ 829.00 | |
50 mg | In stock | $ 1,150.00 | |
100 mg | In stock | $ 1,550.00 | |
500 mg | In stock | $ 2,970.00 |
Description | USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM). USP15-IN-1 showed high antiproliferative activity against non-small cell lung cancer and leukemia cells. USP15 is an interacting protein of cGAS, and USP15 can promote cGAS to recognize DNA and activate downstream signaling pathways. |
Targets&IC50 | USP15:3.76 μM |
In vitro | USP15-IN-1 (0.001-5 μM; 48 h) demonstrates significant inhibitory effects on the proliferation of non-small cell lung carcinoma and leukemia cells, as reported in.[1] |
Molecular Weight | 377.44 |
Formula | C22H23N3O3 |
CAS No. | 2260826-16-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (238.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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USP15-IN-1 2260826-16-0 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB inhibitor inhibit