Odapipam

Name: Odapipam
Brand: TargetMol
SKU: T12288
Rating: 4.5 (1 reviews)

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Catalog No. T12288Cas No. 131796-63-9

Alias NNC 756

Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).

Odapipam

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Catalog No. T12288Alias NNC 756Cas No. 131796-63-9

Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,220	6-8 weeks	6-8 weeks
50 mg	$1,590	6-8 weeks	6-8 weeks
100 mg	$2,430	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).
In vivo	The metabolic pathway of Odapipam in phenobarbital-induced rat liver microsomes has been examined, revealing the formation of five distinct metabolites during its incubation. Analysis of the electron-ionization (EI+) mass spectra identified these metabolites as N-desmethyl-Odapipam, 1-hydroxy-Odapipam, two isomers of 3′-hydroxy-Odapipam, and a dehydrogenated metabolite within the dihydrobenzofuran moiety[1].
Synonyms	NNC 756

Chemical Properties

Molecular Weight	329.82
Formula	C₁₉H₂₀ClNO₂
Cas No.	131796-63-9
Smiles	CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1cccc2CCOc12
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc