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Mal-amido-PEG7-acid

Name: Mal-amido-PEG7-acid
Brand: TargetMol
SKU: T15960
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15960Cas No. 2112731-42-5

Alias Mal-NH-PEG7-COOH, Maleimide-NH-PEG7-CH2CH2COOH

Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Mal-amido-PEG7-acid

🥰Excellent

Catalog No. T15960Alias Mal-NH-PEG7-COOH, Maleimide-NH-PEG7-CH2CH2COOHCas No. 2112731-42-5

Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Pack Size	Price	Availability
1 mg	$82	In Stock
5 mg	$183	In Stock
10 mg	$272	In Stock
25 mg	$413	In Stock
50 mg	$580	In Stock
100 mg	$777	In Stock
200 mg	$1,030	In Stock

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Batch Information

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Purity:≥98%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
In vitro	PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1].
Synonyms	Mal-NH-PEG7-COOH, Maleimide-NH-PEG7-CH2CH2COOH

Chemical Properties

Molecular Weight	548.58
Formula	C₂₄H₄₀N₂O₁₂
Cas No.	2112731-42-5
Smiles	C(CC(NCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)N1C(=O)C=CC1=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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