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PDGF-BB Protein, Rat, Recombinant

(Synonyms: SSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis) Copy Product Info

Synonyms: SSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis

Catalog No. TMPS-00117 Copy Product Info
PDGF-BB Protein, Rat, Recombinant is expressed in E. coli. The accession number is Q05028.
PDGF-BB Protein, Rat, Recombinant
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$98-In Stock
10 μg$170-In Stock
20 μg$2487-10 days7-10 days
50 μg$423-In Stock
100 μg$6827-10 days7-10 days
200 μg$1,0807-10 days7-10 days
500 μg$1,9807-10 days7-10 days
1 mg$3,3907-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as analyzed by SDS-PAGE
Appearance:Lyophilized powder
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Product Introduction

Bioactivity
Bioactivity
ED 50 < 2.0 ng/ml, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 5.0 × 10 5 units/mg.
Description
PDGF-BB Protein, Rat, Recombinant is expressed in E. coli. The accession number is Q05028.
Species
Rat
Expression System
E. coli
TagTag Free
Accession NumberQ05028
ConstructionSer74-Thr182
Protein Purity
> 95% as determined by SDS-PAGE
Endotoxin< 0.2 EU/μg of protein as determined by the LAL method.
FormulationLyophilized after extensive dialysis against 20 mM acetic acid.
ReconstitutionIt is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in 20 mM acetic acid up to 100 μg/ml.
Stability & StorageUpon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsSSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis
Research Background
Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. In vivo, PDGF-BB is mainly produced in heart and placenta, and predominantly expressed by osteoblasts, fibroblasts, smooth muscle cells, and glial cells. An inactive precursor of PDGF-BB is produced in the endoplasmic reticulum and then activated by a proprotein convertase after secretion. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic. Therefore, PDGF-BB and its related pathways are potential pharmacological targets.
Chemical Properties
Molecular Weight~24.6 kDa (Non-reducing conditions)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Related Tags: PDGF-BB Protein, Rat, Recombinant chemical structure | PDGF-BB Protein, Rat, Recombinant molecular weight