PDGF-BB Protein, Rat, Recombinant

Name: PDGF-BB Protein, Rat, Recombinant
Brand: TargetMol
SKU: TMPS-00117
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: SSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis) Copy Product Info

Synonyms: SSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis

Catalog No. TMPS-00117 Copy Product Info

PDGF-BB Protein, Rat, Recombinant is expressed in E. coli. The accession number is Q05028.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	-	In Stock
10 µg	$170	-	In Stock
20 µg	$248	7-10 days	7-10 days
50 µg	$423	-	In Stock
100 µg	$682	7-10 days	7-10 days
200 µg	$1,080	7-10 days	7-10 days
500 µg	$1,980	7-10 days	7-10 days
1 mg	$3,390	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:> 95% as analyzed by SDS-PAGE

Appearance:Lyophilized powder

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 2.0 ng/ml, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 5.0 × 10 5 units/mg.
Description	PDGF-BB Protein, Rat, Recombinant is expressed in E. coli. The accession number is Q05028.
Species	Rat
Expression System	E. coli
Tag	Tag Free
Accession Number	Q05028
Construction	Ser74-Thr182
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized after extensive dialysis against 20 mM acetic acid.
Reconstitution	It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in 20 mM acetic acid up to 100 μg/ml.
Synonyms	SSV, SIS, platelet derived growth factor subunit B, PDGFBB, PDGF-2, PDGF2, IBGC5, c-sis
Research Background	Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. In vivo, PDGF-BB is mainly produced in heart and placenta, and predominantly expressed by osteoblasts, fibroblasts, smooth muscle cells, and glial cells. An inactive precursor of PDGF-BB is produced in the endoplasmic reticulum and then activated by a proprotein convertase after secretion. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic. Therefore, PDGF-BB and its related pathways are potential pharmacological targets.

Chemical Properties

Molecular Weight

~24.6 kDa (Non-reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.