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TOPBioactivityChemical infoStorage&SolubilityCalculator

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin

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Catalog No. T203271Cas No. 39227-28-6
Alias 1,2,3,4,7,8-HxCDD

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzodioxin (PCDD) congener. At the highest dose (10,000 μg/kg), it can cause hepatic pallor (fatty liver), gastrointestinal bleeding, and early mortality in H/W and A strain rats. Additionally, 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin induces liver sinusoidal dilatation and can lead to severe purpura in B strain rats.

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin

😃Good
Catalog No. T203271Alias 1,2,3,4,7,8-HxCDDCas No. 39227-28-6
1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzodioxin (PCDD) congener. At the highest dose (10,000 μg/kg), it can cause hepatic pallor (fatty liver), gastrointestinal bleeding, and early mortality in H/W and A strain rats. Additionally, 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin induces liver sinusoidal dilatation and can lead to severe purpura in B strain rats.
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzodioxin (PCDD) congener. At the highest dose (10,000 μg/kg), it can cause hepatic pallor (fatty liver), gastrointestinal bleeding, and early mortality in H/W and A strain rats. Additionally, 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin induces liver sinusoidal dilatation and can lead to severe purpura in B strain rats.
Synonyms1,2,3,4,7,8-HxCDD
Chemical Properties
Molecular Weight390.86
FormulaC12H2Cl6O2
Cas No.39227-28-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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