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Anti-Phospho-PIK3R1 (Tyr467, 199) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PIK3R1 (Tyr467, 199). Anti-Phospho-PIK3R1 (Tyr467, 199) Polyclonal Antibody can be used in WB,IF,IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $216 | 7-10 days | |
100 μL | $317 | 7-10 days |
Description | Anti-Phospho-PIK3R1 (Tyr467, 199) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PIK3R1 (Tyr467, 199). Anti-Phospho-PIK3R1 (Tyr467, 199) Polyclonal Antibody can be used in WB,IF,IHC. |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Application | |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Appearance | Liquid |
Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y) derived from Human PI3 Kinase p85/p55 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 55, 85 kDa. |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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