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Synonyms: Transcription factor 21, TCF-21, TCF21, Podocyte-expressed 1, POD1, POD 1, Epicardin, Class A basic helix-loop-helix protein 23, Capsulin, bHLHa23
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-POD1 Polyclonal Antibody is a Rabbit antibody targeting MPO. Anti-POD1 Polyclonal Antibody can be used in WB. |
| Synonyms | Transcription factor 21, TCF-21, TCF21, Podocyte-expressed 1, POD1, POD 1, Epicardin, Class A basic helix-loop-helix protein 23, Capsulin, bHLHa23 |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The basic helix-loop-helix (bHLH) class of transcription factors govern cell fate determination by controlling a variety of cellular differentiation processes. POD-1 (podocyte-expressed 1, also designated capsulin or epicardin) is a nuclear bHLH protein that is involved in the specification of select mesodermal cell populations associated with heart, cranial skeletal muscle, gut and urogenital system. POD-1 is selectively expressed in mesenchymal cells at sites of epithelial-mesenchymal interaction in the kidney, lung, intestine, pancreas and the epicardium, which gives rise to the coronary arteries. This epithelial-mesenchymal interaction is involved in the formation of numerous internal organs. POD-1 is also expressed in the mesothelium that gives rise to the spleen and in cells that give rise to smooth muscle. In addition to its role in kidney morphogenesis and spleen organogenesis, POD-1 may play a role in the development and sex determination of the mammalian gonad. |
| Immunogen | KLH conjugated synthetic peptide: human TCF-21 |
| Antigen Species | Human |
| Gene Name | TCF21 |
| Gene ID | |
| Protein Name | Transcription factor 21 |
| Uniprot ID | |
| Biology Area | Transcription factors/regulators,HLH,Transcription Factors |
| Function | Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May play a role in the specification or differentiation of one or more subsets of epicardial cell types. |
| Molecular Weight | Theoretical: 20 kDa. Actual: 26 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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