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Fropofol

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Catalog No. T24074Cas No. 87591-05-7
Alias 2-fluoro-1,3-diisopropylbenzene

Fropofol (2-fluoro-1,3-diisopropylbenzene) is a non-anesthetic small molecule that specifically reduces myocardial contractility and inhibits myofilament contraction. It can be used in research on hypertrophic cardiomyopathy and cardiovascular diseases.

Fropofol

Fropofol

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Purity: 97.86%
Catalog No. T24074Alias 2-fluoro-1,3-diisopropylbenzeneCas No. 87591-05-7
Fropofol (2-fluoro-1,3-diisopropylbenzene) is a non-anesthetic small molecule that specifically reduces myocardial contractility and inhibits myofilament contraction. It can be used in research on hypertrophic cardiomyopathy and cardiovascular diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$293-In Stock
5 mg$722-In Stock
10 mg$987-In Stock
25 mg$1,520-In Stock
50 mg$1,980-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:97.86%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Fropofol (2-fluoro-1,3-diisopropylbenzene) is a non-anesthetic small molecule that specifically reduces myocardial contractility and inhibits myofilament contraction. It can be used in research on hypertrophic cardiomyopathy and cardiovascular diseases.
Synonyms2-fluoro-1,3-diisopropylbenzene
Chemical Properties
Molecular Weight180.26
FormulaC12H17F
Cas No.87591-05-7
SmilesFC=1C(=CC=CC1C(C)C)C(C)C
Relative Density.0.930 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture,store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 18.18 mg/mL (100.85 mM), Sonication is recommended.
Ethanol: 18.18 mg/mL (100.85 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM5.5475 mL27.7377 mL55.4754 mL277.3771 mL
5 mM1.1095 mL5.5475 mL11.0951 mL55.4754 mL
10 mM0.5548 mL2.7738 mL5.5475 mL27.7377 mL
20 mM0.2774 mL1.3869 mL2.7738 mL13.8689 mL
50 mM0.1110 mL0.5548 mL1.1095 mL5.5475 mL
100 mM0.0555 mL0.2774 mL0.5548 mL2.7738 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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