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TargetMol | Compound Library

Anti-Cancer Approved Drug Library

Catalog No. L2110

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy,however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 1920 approved anti-cancer drugs based on published literatures and database to form this collection that can be used as positive controls in biological cancer investigation and cancer correlation study.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2110

Anti-Cancer Approved Drug Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1920 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
  • These FDA, EMA, or NMPA approved anti-cancer drugs have annotated bioactivity, safety, and bioavailability;
  • Effective tool for cancer research and drug repurposing screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc., in lung cancer, breast cancer, leukemia, lymphoma, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
Endogenous Metabolite
Antibacterial
Adrenergic Receptor
5-HT Receptor
Antibiotic
COX
Dopamine Receptor
Histamine Receptor
Potassium Channel
DNA/RNA Synthesis
Parasite
Sodium Channel
Calcium Channel
ROS
NF-κB
AChR
Glucocorticoid Receptor
Cytochromes P450
Reactive Oxygen Species
HIV Protease
Antifungal
EGFR
VEGFR
Estrogen/progestogen Receptor
GABA Receptor
Estrogen Receptor/ERR
Ferroptosis
Virus Protease
SARS-CoV
Influenza Virus
c-Kit
Topoisomerase
Mitophagy
PPAR
Akt
Nucleoside Antimetabolite/Analog
Serotonin Transporter
TNF
PDGFR
Microtubule Associated
Interleukin
iGluR
Dehydrogenase
Prostaglandin Receptor
ERK
PDE
p38 MAPK
JAK
HDAC
c-Met/HGFR
FGFR
HSV
STAT
Norepinephrine
ATPase
Androgen Receptor
RAAS
Proton pump
Caspase
Bcr-Abl
HBV
mTOR
TRP/TRPV Channel
FLT
DNA Alkylator/Crosslinker
MMP
Opioid Receptor
Drug Metabolite
Adenosine Receptor
Bcl-2 Family
Src
Tyrosine Kinases
PI3K
TLR
Progesterone Receptor
Ras
JNK
CDK
ALK
Cholinesterase (ChE)
PKC
MEK
P-gp
AMPK
Wnt/beta-catenin
Raf
Nrf2
NO Synthase
GNRH Receptor
PARP
HIF/HIF Prolyl-Hydroxylase
Beta Amyloid
MAO
NMDAR
Trk receptor
Carbonic Anhydrase
SGLT
Retinoid Receptor
MRP
Antifolate
DHFR
c-RET
BTK
Reverse Transcriptase
ROS Kinase
Mitochondrial Metabolism
ABC Transporter
CFTR
HCV Protease
HMG-CoA Reductase
GSK-3
HSP
ADC Cytotoxin
Angiotensin-converting Enzyme (ACE)
CaMK
Anti-infection
Monoamine Oxidase
Glutathione Peroxidase
Phosphatase
Antifection
Lipoxygenase
P2Y Receptor
IL Receptor
S1P Receptor
Kras
HER
ROCK
Histone Methyltransferase
PKA
DNA Alkylation
Endothelin Receptor
IκB/IKK
Phospholipase
Neurokinin receptor
GluR
Sigma receptor
NADPH
DNA Methyltransferase
Thrombin
FXR
Guanylate cyclase
Tyrosinase
LPL Receptor
GPCR
Isocitrate Dehydrogenase (IDH)
Vasopressin Receptor
DPP-4
GPCR19
Monoamine Transporter
DNA
ribosome
Transferase
Antiviral
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P2X Receptor
Reductase
Hedgehog/Smoothened
TAM Receptor
Aromatase
Oxytocin Receptor
HIF
NOD
Gamma-secretase
c-Fms
IGF-1R
Leukotriene Receptor
MDM-2/p53
Amino Acids and Derivatives
Serine Protease
Antioxidant
Hydroxylase
Annexin A
Molecular Glues
NOD-like Receptor (NLR)
Melatonin Receptor
Serine/threonin kinase
Xanthine Oxidase
FKBP
UGT
Ligands for E3 Ligase
Fatty Acid Synthase
PGE Synthase
Proteasome
Smo
Arginase
CaSR
PAK
GST
Melanocortin Receptor
MicroRNA
Immunology/Inflammation related
MAPK
RSV
Syk
glycosidase
RANKL/RANK
MT Receptor
Na-K-Cl cotransporter
AhR
Cysteine Protease
IRE1
Free radical scavengers
Cannabinoid Receptor
Somatostatin
Aurora Kinase
Thrombopoietin Receptor
Aminopeptidase
Cuproptosis
FAK
Integrin
TOPK
Glucosidase
TGF-beta/Smad
Decarboxylase
Adenosine Deaminase
IKZF
Na+/Ca2+ Exchanger
Photosensitizer
Rho
Ephrin Receptor
GHSR
Gap Junction Protein
IRAK
PD-1/PD-L1
ROR
Ligands for Target Protein for PROTAC
Hexokinase
PANoptosis
OAT
PLK
Complement System
LTR
Histone Demethylase
PERK
NR4A
PROTAC Linker
FAAH
CCR
ATP Citrate Lyase
YAP
IFNAR
Necroptosis
GRK
Telomerase
NOS
Monocarboxylate transporter
Aryl Hydrocarbon Receptor
LDL
DNA gyrase
CXCR
CGRP Receptor
CRM1
Adenylate cyclase
Protease-activated Receptor
Thyroid hormone receptor(THR)
Tie-2
Cholecystokinin Receptor
CSF-1R
Epigenetic Reader Domain
Beta-Secretase
FOXO
Vitamin
PGC-1α
Mdm2
gp120/CD4
Factor Xa
c-Myc
Liver X Receptor
HCN Channel
cAMP
PAI-1
Platelet aggregation
Lipase
Cell Cycle Arrest
PAFR
MTH1
Glucagon Receptor
HCAR
Chk
DUB
Hydrogenase
VDA
ATG
IAP
Adiponectin Receptor
Sirtuin
Casein Kinase
Imidazoline Receptor
BACE
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OCT
Hck
IDO
Arp2/3 Complex
Lipid
PDK
S6 Kinase
RAR/RXR
Bradykinin Receptor
PTEN
Huntingtin
STING
GluCls
Pyroptosis
NADPH-oxidase
p53
MIF
RIP kinase
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
BCRP
ASK
NPC1L1
DNA-PK
Glutathione reductase
Acyltransferase
Neprilysin
Ferroportin

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