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MPO
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Catalog No. T19972Cas No. 1011-51-4
Alias 5-(4'-Methoxyphenyl)-oxazole
MPO (5-(4'-Methoxyphenyl)-oxazole) is an inhibitor of the hatch and growth of Caenorhabditis elegans.
MPO
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Purity: 99.86%
Catalog No. T19972Alias 5-(4'-Methoxyphenyl)-oxazoleCas No. 1011-51-4
MPO (5-(4'-Methoxyphenyl)-oxazole) is an inhibitor of the hatch and growth of Caenorhabditis elegans.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $82 | In Stock | In Stock | |
| 5 mg | $183 | In Stock | In Stock | |
| 10 mg | $272 | In Stock | In Stock | |
| 25 mg | $413 | In Stock | In Stock | |
| 50 mg | $580 | In Stock | In Stock | |
| 100 mg | $777 | In Stock | In Stock | |
| 200 mg | $1,030 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $139 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.86%
Appearance:Solid
Color:White
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Product Introduction
MPO AI Summary
MPO exhibits a range of bioactivities. It shows 100% inhibition of egg hatch newly spawned by adult Caenorhabditis elegans at 17 μM on day 3 and inhibits the growth of adult Caenorhabditis elegans with a minimum inhibitory concentration (MIC) of 34,000 nM on day 3. Additionally, it inhibits egg hatch of adult Caenorhabditis elegans at a MIC of 17,000 nM on day 3. This compound also displays antimicrobial activity against Magnaporthe oryzae with an EC50 of 4,000 nM after 48 hours at 28°C but demonstrates no significant antimicrobial activity against Escherichia coli, Staphylococcus aureus, Aspergillus fumigatus, Candida albicans, Plasmodium falciparum K1, nor does it inhibit various enzymes in Caenorhabditis elegans at the tested concentrations. Regarding cytotoxicity, the compound exhibits activity against human HeLa cells with an EC50 of 30,000 nM after 48 hours, and it shows cytotoxicity against human MDA-MB-231, MDA-MB-453, HCC1937, HCC70, and BT549 cells with a growth inhibition (GI50) value greater than 100,000 nM over 48 to 96 hours, as assessed by the SRB method..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | MPO (5-(4'-Methoxyphenyl)-oxazole) is an inhibitor of the hatch and growth of Caenorhabditis elegans. |
| Synonyms | 5-(4'-Methoxyphenyl)-oxazole |
| Molecular Weight | 175.18 |
| Formula | C10H9NO2 |
| Cas No. | 1011-51-4 |
| Smiles | O(C)C1=CC=C(C=C1)C2=CN=CO2 |
| Relative Density. | 1.132 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 9 mg/mL (51.38 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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