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TOPBioactivityChemical infoStorage&SolubilityCalculator

5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE

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Catalog No. T8912Cas No. 17899-49-9

5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.

5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE

5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE

😃Good
Purity: 99.03%
Catalog No. T8912Cas No. 17899-49-9
5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$31In StockIn Stock
10 mg$44In StockIn Stock
25 mg$85In StockIn Stock
50 mg$121In StockIn Stock
100 mg$181In StockIn Stock
200 mg$269-In Stock
1 mL x 10 mM (in DMSO)$34In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.03%
Appearance:Solid
Color:Yellow
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COA HPLC HNMR LCMS

Product Introduction

Bioactivity
Description
5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.
Chemical Properties
Molecular Weight183.27
FormulaC8H13N3S
Cas No.17899-49-9
SmilesCCN1CCC2=C(C1)SC(N)=N2
Relative Density.1.222g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 22.5 mg/mL (122.77 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.4564 mL27.2822 mL54.5643 mL272.8215 mL
5 mM1.0913 mL5.4564 mL10.9129 mL54.5643 mL
10 mM0.5456 mL2.7282 mL5.4564 mL27.2822 mL
20 mM0.2728 mL1.3641 mL2.7282 mL13.6411 mL
50 mM0.1091 mL0.5456 mL1.0913 mL5.4564 mL
100 mM0.0546 mL0.2728 mL0.5456 mL2.7282 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PLK15ETHYL4,5,6,7TETRAHYDROTHIAZOLO[5,4C]PYRIDIN2YLAMINE5 ETHYL 4,5,6,7 TETRAHYDRO THIAZOLO[5,4 C]PYRIDIN 2 YLAMINE
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