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Anti-GALNT13 Polyclonal Antibody is a Rabbit antibody targeting GALNT13. Anti-GALNT13 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
| Description | Anti-GALNT13 Polyclonal Antibody is a Rabbit antibody targeting GALNT13. Anti-GALNT13 Polyclonal Antibody can be used in WB. |
| Synonyms | UDP N acetyl alpha D galactosamine:polypeptide, UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13, Protein UDP acetylgalactosaminyltransferase 13, pp GaNTase 13, Polypeptide GalNAc transferase 13, N acetylgalactosaminyltransferase 13, GLT13, GalNAc-T13, GalNAc transferase 13 |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow,Rabbit,Sheep) |
| Verified Activity | Sample: VSC4.1 Cell (Rat) Lysate at 40 μg Primary: Anti-GALNT13 (TMAB-00737) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 64 kDa Observed band size: 62 kDa ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Golgi apparatus membrane; Single pass type II membrane protein. |
| Tissue Specificity | Specifically expressed in neuronal cells. Expressed in fetal brain, whole adult brain, cerebral cortex and cerebellum. Not expressed in other tissues tested. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells. |
| Immunogen | KLH conjugated synthetic peptide: human GALNT13/GalNAc-T13 |
| Antigen Species | Human |
| Gene Name | GALNT13 |
| Gene ID | |
| Protein Name | Polypeptide N-acetylgalactosaminyltransferase 13 |
| Uniprot ID | |
| Function | GALNT13 is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue. It is specifically expressed in neuronal cells; expressed in fetal brain, whole adult brain, cerebral cortex and cerebellum; not expressed in other tissues tested. There are two named isoforms. |
| Molecular Weight | Theoretical: 64 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |

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