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DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc)

(Synonyms: tumor necrosis factor receptor superfamily, member 10b, TRICKB, TRICK2B, TRICK2A, TRAILR2, MK, Ly98, KILLER, DR5) Copy Product Info

Synonyms: tumor necrosis factor receptor superfamily, member 10b, TRICKB, TRICK2B, TRICK2A, TRAILR2, MK, Ly98, KILLER, DR5

Catalog No. TMPY-01452 Copy Product Info
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 41.8 kDa and the accession number is Q9QZM4.

Product Introduction

Bioactivity
Bioactivity
Immobilized human TNFSF10 at 10 μg/ml (100 μl/well) can bind mouse TNFRSF10B-Fch, The EC50 of mouse TNFRSF10B-Fch is 0.07-0.17 μg/ml.
Description
DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 41.8 kDa and the accession number is Q9QZM4.
Species
Mouse
Expression System
HEK293 Cells
TagHis, hFc
Accession NumberQ9QZM4
ConstructionA DNA sequence encoding the extracellular domain of mouse TNFRSF10B (NP_064671.2) (Met 1-Ser 177) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. Predicted N terminal: Asn 53
Protein Purity
> 95 % as determined by SDS-PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymstumor necrosis factor receptor superfamily, member 10b, TRICKB, TRICK2B, TRICK2A, TRAILR2, MK, Ly98, KILLER, DR5
Research Background
Chemical Properties
Molecular Weight41.8 kDa (predicted); 50-55 kDa (reducing condition, due to glycosylation)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) chemical structure | DR5/TRAIL R2 Protein, Mouse, Recombinant (His & hFc) molecular weight