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Pirazolac

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Catalog No. T12484Cas No. 71002-09-0
Alias ZK-76604, ZK76604, SCH376, SCH 376, MY-309, MY309

Pirazolac (ZK-76604) is a novel non-steroidal anti-inflammatory agent for the study of rheumatoid arthritis.

Pirazolac

Pirazolac

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Purity: 97.71%
Catalog No. T12484Alias ZK-76604, ZK76604, SCH376, SCH 376, MY-309, MY309Cas No. 71002-09-0
Pirazolac (ZK-76604) is a novel non-steroidal anti-inflammatory agent for the study of rheumatoid arthritis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$293In StockIn Stock
5 mg$722In StockIn Stock
10 mg$987In StockIn Stock
25 mg$1,520In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:97.71%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Pirazolac (ZK-76604) is a novel non-steroidal anti-inflammatory agent for the study of rheumatoid arthritis.
In vitro
Pirazolac is a non-steroidal anti-inflammatory drug.Pirazolac is able to inhibit the accumulation of prostaglandins in the human gastric mucosa under concentration-dependent conditions, but this inhibition is lower than that of indomethacin and other common non-steroidal anti-inflammatory drugs. This characteristic may explain the lesser gastric damage caused by Pirazolac. [1]
SynonymsZK-76604, ZK76604, SCH376, SCH 376, MY-309, MY309
Chemical Properties
Molecular Weight330.74
FormulaC17H12ClFN2O2
Cas No.71002-09-0
SmilesO=C(O)CC1=NN(C=C1C=2C=CC(Cl)=CC2)C3=CC=C(F)C=C3
Relative Density.1.36g/cm3
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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