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PSMA Protein, Human, Recombinant (Improved, His)
(Synonyms: PSMA, PSM, NAALAdase, NAALAD1, mGCP, GIG27, GCPII, GCP2, FOLH, FGCP) Copy Product InfoSynonyms: PSMA, PSM, NAALAdase, NAALAD1, mGCP, GIG27, GCPII, GCP2, FOLH, FGCP
Catalog No. TMPY-07132 Copy Product Info
PSMA Protein, Human, Recombinant (Improved, His) is expressed in CHO Cells. The accession number is Q04609-1.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $93 | 7-10 days | 7-10 days | |
| 10 μg | $152 | 7-10 days | 7-10 days | |
| 20 μg | $248 | 7-10 days | 7-10 days | |
| 50 μg | $497 | 7-10 days | 7-10 days | |
| 100 μg | $855 | 7-10 days | 7-10 days | |
| 200 μg | $1,460 | 7-10 days | 7-10 days | |
| 500 μg | $2,980 | 7-10 days | 7-10 days | |
| 1 mg | $5,930 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1. Immobilized PSMA Protein, Human, Recombinant (Improved, His) (Cat#TMPY-07132) at 1 μg/mL (100 μL/well) can bind Anti-PSMA Antibody, the EC50 is 5-15 ng/mL. 2. Measured by its ability to hydrolyze the substrate N-acetyl-L-Asp-L-Glu into N-acetyl-L-Asp and L-Glu. The L-Glu product is measured by fluorescence after its derivatization by ortho-phthaldialdehyde. The specific activity is >800 pmol/min/µg. |
| Description | PSMA Protein, Human, Recombinant (Improved, His) is expressed in CHO Cells. The accession number is Q04609-1. |
| Species | Human |
| Expression System | CHO Cells |
| Tag | N-His |
| Accession Number | Q04609-1 |
| Construction | A DNA sequence encoding the Human FOLH1 (NP_004467.1) (Lys44-Ala750) was expressed, with a polyhistidine tag at the N-terminus. |
| Protein Purity | ≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile solution in MES, NaCl, trehalose, CaCl2, MgCl2 and ZnCl2, pH 6.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Please refer to the lot-specific COA. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | PSMA, PSM, NAALAdase, NAALAD1, mGCP, GIG27, GCPII, GCP2, FOLH, FGCP |
| Research Background | Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. FOLH1 is highly expressed in prostate epithelium. It is detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon, brain (at protein level), and the capillary endothelium of a variety of tumors. FOLH1 has both folate hydrolase and N-acetylated alpha linked acidic dipeptidase (NAALADase) activity. It has a preference for tri-alpha-glutamate peptides. Genetic variation in FOLH1 may be associated with low folate levels and consequent hyperhomocysteinemia. This condition can result in increased risk of cardiovascular disease, neural tube defects, and cognitive deficits. FOLH1 also shows a promising role in directed imaging and therapy of recurrent or metastatic disease.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Molecular Weight | 84.29 kDa (predicted); 94.5 kDa (reducing contition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: PSMA Protein, Human, Recombinant (Improved, His) chemical structure | PSMA Protein, Human, Recombinant (Improved, His) molecular weight
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