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Bacopaside X

Name: Bacopaside X
Brand: TargetMol
SKU: TN1424
Price: 57 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. TN1424Cas No. 94443-88-6

Alias Bacopaside VII

Bacopaside X is a triterpenoid saponin isolated from Bacopa monniera that exhibits strong antifungal and anticancer activities by actively suppressing pathogenic fungal growth and tumor progression, demonstrated through inhibition of Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus at MIC values of 50 µg/ml, along with significantly decreasing proliferation in cancer cell lines MDA-MB-231, SHG44, HCT8, A549, and PC3M with IC50 values of 14.3, 15.9, 9.8, 9.7, and 10.1 µM respectively. Bacopaside X additionally reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model when administered at a dose of 50 µmol/kg, indicating substantial therapeutic potential.

Bacopaside X

😃Good

Purity: 99.89%

Catalog No. TN1424Alias Bacopaside VIICas No. 94443-88-6

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$57	-	In Stock
5 mg	$136	-	In Stock
10 mg	$196	-	In Stock
25 mg	$337	-	In Stock
50 mg	$492	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.89%

Appearance:Solid

Color:White

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Bacopaside X is a triterpenoid saponin isolated from Bacopa monniera that exhibits strong antifungal and anticancer activities by actively suppressing pathogenic fungal growth and tumor progression, demonstrated through inhibition of Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus at MIC values of 50 µg/ml, along with significantly decreasing proliferation in cancer cell lines MDA-MB-231, SHG44, HCT8, A549, and PC3M with IC50 values of 14.3, 15.9, 9.8, 9.7, and 10.1 µM respectively. Bacopaside X additionally reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model when administered at a dose of 50 µmol/kg, indicating substantial therapeutic potential.
In vitro	Bacopaside X was tested using in vitro radioligand receptor binding assays (with ³H-SCH 23390 as the ligand), showing its binding affinity for the dopamine D1 receptor (Ki value of 9.06 μM) but no inhibitory activity against acetylcholinesterase (AChE) [1].
Synonyms	Bacopaside VII

Chemical Properties

Molecular Weight	899.07
Formula	C₄₆H₇₄O₁₇
Cas No.	94443-88-6
Smiles	C[C@]12[C@@]34[C@@]([C@@]5([C@@](C3)(OC4)O[C@@H](C=C(C)C)C[C@]5(C)O)[H])(CC[C@@]1([C@]6(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]7[C@H](O[C@@H]8O[C@@H](CO)[C@H](O)[C@H]8O)[C@@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)CO7)CC6)[H])[H])[H]
Relative Density.	1.41

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (88.98 mM), Sonication is recommeded.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1123 mL	5.5613 mL	11.1226 mL	55.6130 mL
5 mM	0.2225 mL	1.1123 mL	2.2245 mL	11.1226 mL
10 mM	0.1112 mL	0.5561 mL	1.1123 mL	5.5613 mL
20 mM	0.0556 mL	0.2781 mL	0.5561 mL	2.7807 mL
50 mM	0.0222 mL	0.1112 mL	0.2225 mL	1.1123 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc