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Bacopaside X

Name: Bacopaside X
Brand: TargetMol
SKU: TN1424
Price: 57 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN1424Cas No. 94443-88-6

Alias Bacopaside VII

Bacopaside X is a triterpenoid saponin isolated from Bacopa monniera that exhibits strong antifungal and anticancer activities by actively suppressing pathogenic fungal growth and tumor progression, demonstrated through inhibition of Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus at MIC values of 50 µg/ml, along with significantly decreasing proliferation in cancer cell lines MDA-MB-231, SHG44, HCT8, A549, and PC3M with IC50 values of 14.3, 15.9, 9.8, 9.7, and 10.1 µM respectively. Bacopaside X additionally reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model when administered at a dose of 50 µmol/kg, indicating substantial therapeutic potential.

Bacopaside X

🥰Excellent

Purity: 99.89%

Catalog No. TN1424Alias Bacopaside VIICas No. 94443-88-6

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$57	-	In Stock
5 mg	$136	-	In Stock
10 mg	$196	-	In Stock
25 mg	$337	-	In Stock
50 mg	$492	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.89%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Bacopaside X is a triterpenoid saponin isolated from Bacopa monniera that exhibits strong antifungal and anticancer activities by actively suppressing pathogenic fungal growth and tumor progression, demonstrated through inhibition of Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus at MIC values of 50 µg/ml, along with significantly decreasing proliferation in cancer cell lines MDA-MB-231, SHG44, HCT8, A549, and PC3M with IC50 values of 14.3, 15.9, 9.8, 9.7, and 10.1 µM respectively. Bacopaside X additionally reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model when administered at a dose of 50 µmol/kg, indicating substantial therapeutic potential.
In vitro	Bacopaside X was tested using in vitro radioligand receptor binding assays (with ³H-SCH 23390 as the ligand), showing its binding affinity for the dopamine D1 receptor (Ki value of 9.06 μM) but no inhibitory activity against acetylcholinesterase (AChE) [1].
Synonyms	Bacopaside VII

Chemical Properties

Molecular Weight	899.07
Formula	C₄₆H₇₄O₁₇
Cas No.	94443-88-6
Smiles	C[C@]12[C@@]34[C@@]([C@@]5([C@@](C3)(OC4)O[C@@H](C=C(C)C)C[C@]5(C)O)[H])(CC[C@@]1([C@]6(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]7[C@H](O[C@@H]8O[C@@H](CO)[C@H](O)[C@H]8O)[C@@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)CO7)CC6)[H])[H])[H]
Relative Density.	1.41
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (88.98 mM), Sonication is recommeded.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1123 mL	5.5613 mL	11.1226 mL	55.6130 mL
5 mM	0.2225 mL	1.1123 mL	2.2245 mL	11.1226 mL
10 mM	0.1112 mL	0.5561 mL	1.1123 mL	5.5613 mL
20 mM	0.0556 mL	0.2781 mL	0.5561 mL	2.7807 mL
50 mM	0.0222 mL	0.1112 mL	0.2225 mL	1.1123 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc