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Acetyl Angiotensinogen (1-14), porcine Acetate is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH. The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $31 | In Stock | In Stock | |
| 25 mg | $41 | In Stock | In Stock | |
| 50 mg | $66 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $48 | In Stock | In Stock |
| Description | Acetyl Angiotensinogen (1-14), porcine Acetate is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH. The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor. |
| In vitro | The renin-angiotensin system?was extracted from blood with 70% acetone and had a short pressor effect.?The renin acted enzymatically on a plasma protein to produce the new substance.? |
| In vivo | The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor.?Pre-angiotensinogen is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure.?The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II.?Angiotensin II is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia[2]. |
| Synonyms | Acetyl Angiotensinogen (1-14), porcine Acetate(66641-26-7 Free base) |
| Molecular Weight | 1861.1 |
| Formula | C89H129N21O23 |
| Smiles | O=C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CNC=N5)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC6=CC=C(C=C6)O)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C.CC(O)=O |
| Relative Density. | no data available |
| Sequence | Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH. |
| Sequence Short | DRVYIHPFHLLVYS |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 162 mg/mL (87.05 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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