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Alacepril

Name: Alacepril
Brand: TargetMol
SKU: T7808
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7808Cas No. 74258-86-9

Alias DU-1219, Cetapril

Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive

Alacepril

🥰Excellent

Purity: 97.78%

Catalog No. T7808Alias DU-1219, CetaprilCas No. 74258-86-9

Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive

Pack Size	Price	Availability
10 mg	$50	In Stock
25 mg	$81	In Stock
50 mg	$122	In Stock
100 mg	$182	In Stock
1 mL x 10 mM (in DMSO)	$55	In Stock

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Purity:97.78%

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive
In vivo	Treatment with alacepril improves functional status and exercise capacity in patients with mild-to-moderate CHF. Neurohormones were favourably influenced by alacepril therapy, with significant decreases in plasma aldosterone, ANP and BNP levels[1].
Synonyms	DU-1219, Cetapril

Chemical Properties

Molecular Weight	406.5
Formula	C₂₀H₂₆N₂O₅S
Cas No.	74258-86-9
Smiles	C([C@@H](CSC(C)=O)C)(=O)N1[C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)CCC1
Relative Density.	1.281g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (67.65 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.92 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4600 mL	12.3001 mL	24.6002 mL	123.0012 mL
5 mM	0.4920 mL	2.4600 mL	4.9200 mL	24.6002 mL
10 mM	0.2460 mL	1.2300 mL	2.4600 mL	12.3001 mL
20 mM	0.1230 mL	0.6150 mL	1.2300 mL	6.1501 mL
50 mM	0.0492 mL	0.2460 mL	0.4920 mL	2.4600 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc