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4-POBN

Name: 4-POBN
Brand: TargetMol
SKU: T26389
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T26389Cas No. 5351-17-7

Alias NSC-640, NSC640, NSC 640, Myeloperoxidase Inhibitor 1, 4-Aminobenzohydrazide, 4-ABAH

4-POBN (Myeloperoxidase Inhibitor 1) is a potent and irreversible inhibitor of myeloperoxidase (IC50 = 0.3 µM). 4-POBN can be used in studies about subacute stroke.

4-POBN

🥰Excellent

Purity: 99.60%

Catalog No. T26389Alias NSC-640, NSC640, NSC 640, Myeloperoxidase Inhibitor 1, 4-Aminobenzohydrazide, 4-ABAHCas No. 5351-17-7

4-POBN (Myeloperoxidase Inhibitor 1) is a potent and irreversible inhibitor of myeloperoxidase (IC50 = 0.3 µM). 4-POBN can be used in studies about subacute stroke.

Pack Size	Price	Availability
200 mg	$34	In Stock
500 mg	$53	In Stock
1 g	$77	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.60%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	4-POBN (Myeloperoxidase Inhibitor 1) is a potent and irreversible inhibitor of myeloperoxidase (IC50 = 0.3 µM). 4-POBN can be used in studies about subacute stroke.
Synonyms	NSC-640, NSC640, NSC 640, Myeloperoxidase Inhibitor 1, 4-Aminobenzohydrazide, 4-ABAH

Chemical Properties

Molecular Weight	151.17
Formula	C₇H₉N₃O
Cas No.	5351-17-7
Smiles	NNC(=O)c1ccc(N)cc1
Relative Density.	1.2100 g/cm3 (Estimated)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (297.68 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.6151 mL	33.0753 mL	66.1507 mL	330.7535 mL
5 mM	1.3230 mL	6.6151 mL	13.2301 mL	66.1507 mL
10 mM	0.6615 mL	3.3075 mL	6.6151 mL	33.0753 mL
20 mM	0.3308 mL	1.6538 mL	3.3075 mL	16.5377 mL
50 mM	0.1323 mL	0.6615 mL	1.3230 mL	6.6151 mL
100 mM	0.0662 mL	0.3308 mL	0.6615 mL	3.3075 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc