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Anti-CXADR/CAR Antibody-PE (7D440)
🥰Excellent
Catalog No. TMAY-01175P
Anti-CXADR/CAR Antibody-PE (7D440) is a PE-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-PE (7D440) can be used in FCM.
Anti-CXADR/CAR Antibody-PE (7D440)
Anti-CXADR/CAR Antibody-PE (7D440)
🥰Excellent
Catalog No. TMAY-01175P
Anti-CXADR/CAR Antibody-PE (7D440) is a PE-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-PE (7D440) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CXADR/CAR Antibody-PE (7D440) is a PE-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-PE (7D440) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7D440 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of human CXADR expression on HT-29 cells. HT-29 cells were stained with PE-conjugated anti-Human CXARD. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CXADR / CAR (rh CXADR / CAR; TMPY-02121; NP_001329.1; Met1-Gly237) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR. |
| Conjucates | PE |
| Others Formats | Unconjugated/FITC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human CXADR / CAR protein (TMPY-02121) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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