Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-PDGFRA Antibody-APC (1K967)
🥰Excellent
Catalog No. TMAY-00967A
Anti-PDGFRA Antibody-APC (1K967) is a APC-conjugated Mouse antibody targeting PDGFRA. Anti-PDGFRA Antibody-APC (1K967) can be used in FCM.
Anti-PDGFRA Antibody-APC (1K967)
Anti-PDGFRA Antibody-APC (1K967)
🥰Excellent
Catalog No. TMAY-00967A
Anti-PDGFRA Antibody-APC (1K967) is a APC-conjugated Mouse antibody targeting PDGFRA. Anti-PDGFRA Antibody-APC (1K967) can be used in FCM.
Product information is being updated, if you want to purchase, please click the bulk custom button.
Bulk & Custom
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PDGFRA Antibody-APC (1K967) is a APC-conjugated Mouse antibody targeting PDGFRA. Anti-PDGFRA Antibody-APC (1K967) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 1K967 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human PDGFRα (CD140a) expression on MG63 cells. Cells were stained with APC-conjugated anti-Human PDGFRα (CD140a). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PDGFRA / CD140a (rh PDGFRA / CD140a; TMPY-01139; NP_006197.1; Met1-Glu524) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfamily of receptor tyrosine kinase (RTKs) with the similar structure characteristics of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular region. PDGFRA is expressed in oligodendrocyte progenitor cells and mesothelial cell, and binds all three ligand isoforms PDGF-AA, PDGF-BB and PDGF-AB with high affinity, whereas PDGFRB dose not bind PDGF-AA. PDGFRA plays an essential role in regulating proliferation, chemotaxis and migration of mesangial cells. Recent studies have indicated that PDGFRA acts as a critical mediator of signaling in testis organogenesis and Leydig cell differentiation, and in addition, particularly important for kidney development. Additionally, PDGFRA is involved in tumor angiogenesis and maintenance of the tumor microenvironment and has been implicated in development and metastasis of Hepatocellular carcinoma (HCC). PDGFRA may represent a potential therapeutic target in thymic tumours. PDGFRA gene amplification rather than gene mutation may be the underlying genetic mechanism driving PDGFRA overexpression in a portion of gliomas.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human PDGFRA / CD140a Protein (TMPY-01139) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-PDGFRA Antibody-APC (1K967) | purchase Anti-PDGFRA Antibody-APC (1K967) | Anti-PDGFRA Antibody-APC (1K967) cost | order Anti-PDGFRA Antibody-APC (1K967)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.