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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Calcium Channel
Dopamine Receptor
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
Antibacterial
GluR
p38 MAPK
TRP/TRPV Channel
Histone Methyltransferase
NF-κB
GPCR
iGluR
Cholinesterase (ChE)
Caspase
Prostaglandin Receptor
JAK
Src
Parasite
Adenosine Receptor
NO Synthase
ERK
Akt
FLT
Opioid Receptor
PKC
ROS
PDGFR
GSK-3
Estrogen Receptor/ERR
MMP
RAAS
TLR
FGFR
c-Met/HGFR
Raf
TNF
CDK
c-Kit
TGF-beta/Smad
COX
Cannabinoid Receptor
Bcr-Abl
HSP
ATPase
ALK
Wnt/beta-catenin
Cytochromes P450
P-gp
PKA
BTK
LPL Receptor
Reactive Oxygen Species
Antibiotic
Interleukin
NMDAR
Estrogen/progestogen Receptor
HIV Protease
Kras
Aurora Kinase
Serotonin Transporter
CCR
ROCK
STAT
Tyrosine Kinases
PI3K
CXCR
Drug Metabolite
Integrin
Neurokinin receptor
IGF-1R
Casein Kinase
P2X Receptor
S1P Receptor
Proton pump
Sigma receptor
DNA/RNA Synthesis
Trk receptor
FAK
Antifungal
c-RET
IL Receptor
Angiotensin-converting Enzyme (ACE)
Influenza Virus
Hedgehog/Smoothened
TAM Receptor
PDE
JNK
SARS-CoV
PPAR
c-Fms
Ferroptosis
Norepinephrine
CFTR
Bcl-2 Family
Virus Protease
Chloride channel
mTOR
HER
transporter
Syk
Cysteine Protease
Protease-activated Receptor
AMPK
Beta Amyloid
Leukotriene Receptor
cAMP
Cholecystokinin Receptor
Endothelin Receptor
Epigenetic Reader Domain
Glucagon Receptor
PARP
Mitophagy
P2Y Receptor
DYRK
ROS Kinase
SGLT
Anti-infection
Melanocortin Receptor
MRP
OX Receptor
LPA Receptor
MEK
NOS
Smo
Neuropeptide Y Receptor
Vasopressin Receptor
Lipoxygenase
Guanylate cyclase
Antioxidant
S6 Kinase
GNRH Receptor
Bradykinin Receptor
Rho
Tyrosinase
ABC Transporter
HSV
Phospholipase
CaMK
GTPase
Ephrin Receptor
Mitochondrial Metabolism
HCV Protease
HDAC
Adenylate cyclase
GPCR19
Serine Protease
MAPK
Arrestin
Phosphatase
Nrf2
PERK
Monoamine Transporter
Neurotensin Receptor
BCRP
Microtubule Associated
CSF-1R
Monoamine Oxidase
HIF/HIF Prolyl-Hydroxylase
CaSR
GHSR
Monocarboxylate transporter
Somatostatin
Discoidin Domain Receptor (DDR)
Dehydrogenase
PAFR
Serine/threonin kinase
Immunology/Inflammation related
MAO
Melatonin Receptor
Antifection
PGE Synthase
IκB/IKK
GRK
Antiviral
Na+/Ca2+ Exchanger
Oxytocin Receptor
MDM-2/p53
Topoisomerase
Tie-2
Glucocorticoid Receptor
Bombesin Receptor
OAT
CRFR
FXR
Carbonic Anhydrase
HBV
Sirtuin
PYK2
Apelin receptor
CGRP Receptor
MLK
Nucleoside Antimetabolite/Analog
RIP kinase
Glucosidase
Beta-Secretase
OCT
NOD-like Receptor (NLR)
LTR
TSH Receptor
Hydroxylase
CRM1
Melanin-concentrating Hormone Receptor (MCHR)
Neuropeptide FF Receptor
Acyltransferase
Pim
Annexin A
MT Receptor
Chk
Progesterone Receptor
HCN Channel
HIF
IRAK
Aryl Hydrocarbon Receptor
LDL
p53
Histone Demethylase
Glutaminase
Androgen Receptor
Aquaporin
HMG-CoA Reductase
Reductase
Myosin
Transferase
BACE
DNA Methyltransferase
Thrombin
RSV
c-Myc
MyD88
Glutathione Peroxidase
PTEN
PROTACs
FAAH
glycosidase
DNA
Imidazoline Receptor
Fatty Acid Synthase
NPC1L1
FOXO
IFNAR
NADPH
AhR
Gamma-secretase
PLK
PAK
Histone Acetyltransferase
GST
Reverse Transcriptase
Platelet aggregation
NOD
OXPHOS
Free radical scavengers
Pyroptosis
VDAC
IAP
Adiponectin Receptor
Survivin
Thyroid hormone receptor(THR)
Hck
Stearoyl-CoA Desaturase (SCD)
ACK1
PDK
SGK
Amino Acids and Derivatives
Liver X Receptor
PAI-1
PD-1/PD-L1
Cadherin
MRGPR
LRRK2
ribosome
CRISPR/Cas9
Transaminase
UGT
Proteasome
Succinate Receptor 1 (SUCNR1)
Kisspeptin
YAP
Na-K-Cl cotransporter
Lipid
ROR
Dynamin
PANoptosis
DUB
EBI2/GPR183
Arginase
gp120/CD4
Photosensitizer
AIM2
MELK
Aromatase
IRE1
PACAP
DNA gyrase
STING
GluCls
Retinoid Receptor
RXFP receptor
NADPH-oxidase
NR4A
E1/E2/E3 Enzyme
PROTAC Linker
ATP Citrate Lyase
Porcupine
Antifolate
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
Cuproptosis
DHFR
DNA-PK
Piezo Channel
Necroptosis
IDO
Lipase
Cell Cycle Arrest
Glucokinase
HCAR
MNK
Complement System
IKZF
Mdm2
GSNOR
ASCT
NAMPT
Carboxypeptidase
Gap Junction Protein
Lysosomal Autophagy
RAR/RXR
Neuropeptide W
Amylase
FABP
Huntingtin
Acetyl-CoA Carboxylase
FKBP
GPX
PKM
GDNF
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
cGAS
Hippo pathway
ASBT
Glutaminyl Cyclase
MIF
PAD
Thrombopoietin Receptor
Aminopeptidase
Urea Transporter
DAPK
p97
Kinesin
Taste receptor
TOPK
AAK1
FLAP
Motilin Receptor
DNA Alkylation
Neprilysin
ATM/ATR
Adenosine Deaminase
Liposome
RANKL/RANK
Phosphorylase
Telomerase
MicroRNA
Galectin
LIM Kinase
Haspin Kinase
DPP-4
Orphan Receptor
Protease
IGF-2R
Sodium-dependent phosphate transporter
ADC Cytotoxin

Keywords