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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Calcium Channel
Dopamine Receptor
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
Antibacterial
GluR
TRP/TRPV Channel
p38 MAPK
Histone Methyltransferase
NF-κB
GPCR
iGluR
Cholinesterase (ChE)
Caspase
JAK
Prostaglandin Receptor
Src
Parasite
Adenosine Receptor
NO Synthase
ERK
Akt
FLT
PKC
ROS
Opioid Receptor
PDGFR
Estrogen Receptor/ERR
GSK-3
MMP
RAAS
TLR
FGFR
Raf
c-Met/HGFR
TNF
CDK
c-Kit
TGF-beta/Smad
COX
HSP
Cannabinoid Receptor
Bcr-Abl
ATPase
ALK
Wnt/beta-catenin
Cytochromes P450
PKA
P-gp
LPL Receptor
Reactive Oxygen Species
NMDAR
Antibiotic
Interleukin
Estrogen/progestogen Receptor
Kras
HIV Protease
Aurora Kinase
Serotonin Transporter
CCR
ROCK
STAT
Tyrosine Kinases
PI3K
Integrin
CXCR
Drug Metabolite
IGF-1R
Casein Kinase
Neurokinin receptor
S1P Receptor
P2X Receptor
Sigma receptor
Proton pump
DNA/RNA Synthesis
Antifungal
Trk receptor
FAK
Hedgehog/Smoothened
c-RET
IL Receptor
SARS-CoV
TAM Receptor
Influenza Virus
JNK
Angiotensin-converting Enzyme (ACE)
PDE
PPAR
c-Fms
CFTR
Norepinephrine
Virus Protease
Ferroptosis
Bcl-2 Family
HER
mTOR
transporter
Chloride channel
Syk
AMPK
Beta Amyloid
Cysteine Protease
Protease-activated Receptor
Endothelin Receptor
Leukotriene Receptor
Cholecystokinin Receptor
cAMP
Epigenetic Reader Domain
PARP
Mitophagy
P2Y Receptor
Glucagon Receptor
DYRK
ROS Kinase
SGLT
Anti-infection
Melanocortin Receptor
Smo
LPA Receptor
MEK
MRP
OX Receptor
Antioxidant
Neuropeptide Y Receptor
NOS
Vasopressin Receptor
Lipoxygenase
S6 Kinase
Guanylate cyclase
Bradykinin Receptor
BTK
ABC Transporter
HSV
GNRH Receptor
Rho
CaMK
Tyrosinase
GTPase
Ephrin Receptor
Phospholipase
Mitochondrial Metabolism
GPCR19
HDAC
HCV Protease
Adenylate cyclase
Serine Protease
MAPK
PERK
Monoamine Transporter
CSF-1R
Monoamine Oxidase
HIF/HIF Prolyl-Hydroxylase
Arrestin
Phosphatase
Nrf2
Neurotensin Receptor
BCRP
CaSR
GHSR
Dehydrogenase
PAFR
Monocarboxylate transporter
Discoidin Domain Receptor (DDR)
Microtubule Associated
Immunology/Inflammation related
Serine/threonin kinase
Somatostatin
MAO
IκB/IKK
GRK
Antiviral
Melatonin Receptor
Antifection
PGE Synthase
Na+/Ca2+ Exchanger
Oxytocin Receptor
MDM-2/p53
Tie-2
Glucocorticoid Receptor
Bombesin Receptor
OAT
Topoisomerase
Carbonic Anhydrase
HBV
Sirtuin
CRFR
Apelin receptor
FXR
PYK2
Nucleoside Antimetabolite/Analog
Glucosidase
Beta-Secretase
OCT
NOD-like Receptor (NLR)
CGRP Receptor
MLK
RIP kinase
LTR
TSH Receptor
Hydroxylase
Melanin-concentrating Hormone Receptor (MCHR)
Neuropeptide FF Receptor
Acyltransferase
Pim
Annexin A
MT Receptor
Chk
CRM1
Glutaminase
Histone Demethylase
Progesterone Receptor
HCN Channel
HIF
IRAK
Proteasome
Reductase
Myosin
Transferase
BACE
DNA Methyltransferase
Thrombin
RSV
Aryl Hydrocarbon Receptor
p53
Fatty Acid Synthase
Androgen Receptor
Aquaporin
HMG-CoA Reductase
PROTACs
FAAH
glycosidase
DNA
Imidazoline Receptor
c-Myc
NOD
NPC1L1
FOXO
IFNAR
NADPH
AhR
Gamma-secretase
PLK
MyD88
Glutathione Peroxidase
LDL
PTEN
VDAC
IAP
Adiponectin Receptor
PAK
Histone Acetyltransferase
GST
Reverse Transcriptase
Platelet aggregation
Thyroid hormone receptor(THR)
Hck
Stearoyl-CoA Desaturase (SCD)
ACK1
PDK
SGK
Amino Acids and Derivatives
OXPHOS
Free radical scavengers
Pyroptosis
Survivin
ribosome
CRISPR/Cas9
Liver X Receptor
PAI-1
PD-1/PD-L1
Succinate Receptor 1 (SUCNR1)
Kisspeptin
YAP
Na-K-Cl cotransporter
Lipid
ROR
Dynamin
DUB
Cadherin
MRGPR
LRRK2
Transaminase
UGT
NR4A
E1/E2/E3 Enzyme
PROTAC Linker
ATP Citrate Lyase
Porcupine
EBI2/GPR183
Arginase
gp120/CD4
Photosensitizer
AIM2
MELK
Aromatase
DHFR
DNA-PK
Piezo Channel
Necroptosis
IDO
Lipase
Cell Cycle Arrest
Glucokinase
HCAR
MNK
Complement System
IRE1
PACAP
DNA gyrase
STING
GluCls
Retinoid Receptor
RXFP receptor
NADPH-oxidase
Antifolate
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
Cuproptosis
IKZF
GDNF
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
cGAS
Hippo pathway
Mdm2
GSNOR
ASCT
NAMPT
Carboxypeptidase
Gap Junction Protein
Lysosomal Autophagy
Taste receptor
TOPK
AAK1
FLAP
Motilin Receptor
DNA Alkylation
Neprilysin
ATM/ATR
Adenosine Deaminase
Liposome
RANKL/RANK
Phosphorylase
Telomerase
MicroRNA
Galectin
LIM Kinase
Haspin Kinase
Orphan Receptor
Protease
RAR/RXR
Neuropeptide W
Amylase
FABP
Huntingtin
Acetyl-CoA Carboxylase
FKBP
GPX
PKM
ASBT
Glutaminyl Cyclase
MIF
PAD
Thrombopoietin Receptor
Aminopeptidase
Urea Transporter
DAPK
p97
Kinesin
IGF-2R
ADC Cytotoxin
Sodium-dependent phosphate transporter

Keywords