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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Calcium Channel
Dopamine Receptor
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
Antibacterial
GluR
TRP/TRPV Channel
p38 MAPK
Histone Methyltransferase
NF-κB
GPCR
iGluR
Cholinesterase (ChE)
JAK
Caspase
Prostaglandin Receptor
Src
Parasite
NO Synthase
Adenosine Receptor
ERK
Opioid Receptor
FLT
Akt
ROS
PKC
PDGFR
Estrogen Receptor/ERR
GSK-3
MMP
RAAS
FGFR
TLR
Raf
c-Met/HGFR
CDK
c-Kit
TNF
TGF-beta/Smad
COX
Bcr-Abl
HSP
Cannabinoid Receptor
ATPase
ALK
Wnt/beta-catenin
Cytochromes P450
PKA
P-gp
LPL Receptor
NMDAR
Reactive Oxygen Species
Estrogen/progestogen Receptor
Interleukin
Kras
Aurora Kinase
HIV Protease
Serotonin Transporter
Antibiotic
CCR
ROCK
STAT
Tyrosine Kinases
CXCR
Integrin
PI3K
IGF-1R
Drug Metabolite
Neurokinin receptor
Casein Kinase
S1P Receptor
P2X Receptor
Proton pump
Sigma receptor
Antifungal
Trk receptor
FAK
c-RET
DNA/RNA Synthesis
Hedgehog/Smoothened
IL Receptor
Influenza Virus
SARS-CoV
TAM Receptor
JNK
PDE
PPAR
Angiotensin-converting Enzyme (ACE)
Norepinephrine
c-Fms
Ferroptosis
Virus Protease
CFTR
HER
Bcl-2 Family
Chloride channel
transporter
mTOR
Syk
Cysteine Protease
Protease-activated Receptor
AMPK
Endothelin Receptor
Leukotriene Receptor
Beta Amyloid
Cholecystokinin Receptor
Glucagon Receptor
Mitophagy
Epigenetic Reader Domain
P2Y Receptor
PARP
cAMP
SGLT
DYRK
ROS Kinase
OX Receptor
Smo
LPA Receptor
MEK
Anti-infection
Antioxidant
Melanocortin Receptor
MRP
Neuropeptide Y Receptor
S6 Kinase
NOS
Guanylate cyclase
Vasopressin Receptor
Lipoxygenase
BTK
Bradykinin Receptor
Tyrosinase
CaMK
GNRH Receptor
Phospholipase
Mitochondrial Metabolism
GPCR19
ABC Transporter
HSV
GTPase
Rho
Ephrin Receptor
HCV Protease
MAPK
HDAC
Adenylate cyclase
Arrestin
Monoamine Transporter
Neurotensin Receptor
BCRP
CSF-1R
Phosphatase
Serine/threonin kinase
Nrf2
Serine Protease
HIF/HIF Prolyl-Hydroxylase
Monoamine Oxidase
PERK
CaSR
Somatostatin
Discoidin Domain Receptor (DDR)
Microtubule Associated
Monocarboxylate transporter
Immunology/Inflammation related
PAFR
Dehydrogenase
GHSR
Antifection
PGE Synthase
IκB/IKK
Melatonin Receptor
GRK
Antiviral
MAO
Tie-2
OAT
Glucocorticoid Receptor
Bombesin Receptor
Na+/Ca2+ Exchanger
MDM-2/p53
PYK2
FXR
Topoisomerase
Apelin receptor
OCT
Carbonic Anhydrase
HBV
Sirtuin
CRFR
RIP kinase
Glucosidase
Beta-Secretase
CGRP Receptor
MLK
NOD-like Receptor (NLR)
Nucleoside Antimetabolite/Analog
Oxytocin Receptor
CRM1
Glutaminase
Melanin-concentrating Hormone Receptor (MCHR)
Neuropeptide FF Receptor
Acyltransferase
Chk
Pim
Annexin A
MT Receptor
LTR
TSH Receptor
Hydroxylase
Fatty Acid Synthase
Androgen Receptor
Aquaporin
HMG-CoA Reductase
Reductase
Myosin
Aryl Hydrocarbon Receptor
p53
RSV
Transferase
BACE
DNA Methyltransferase
Thrombin
Histone Demethylase
Progesterone Receptor
HCN Channel
HIF
IRAK
Proteasome
NPC1L1
FOXO
MyD88
Glutathione Peroxidase
LDL
PTEN
Gamma-secretase
PLK
IFNAR
NADPH
AhR
PROTACs
FAAH
glycosidase
DNA
Imidazoline Receptor
c-Myc
Platelet aggregation
NOD
Survivin
Thyroid hormone receptor(THR)
OXPHOS
Free radical scavengers
Pyroptosis
Amino Acids and Derivatives
Hck
Stearoyl-CoA Desaturase (SCD)
ACK1
PDK
SGK
VDAC
IAP
Adiponectin Receptor
PAK
Histone Acetyltransferase
GST
Reverse Transcriptase
Transaminase
UGT
Succinate Receptor 1 (SUCNR1)
Kisspeptin
Cadherin
MRGPR
LRRK2
ROR
Dynamin
DUB
YAP
Na-K-Cl cotransporter
Lipid
ribosome
CRISPR/Cas9
Liver X Receptor
PAI-1
PD-1/PD-L1
Antifolate
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
Cuproptosis
DHFR
DNA-PK
AAK1
IRE1
PACAP
DNA gyrase
STING
GluCls
Retinoid Receptor
RXFP receptor
NADPH-oxidase
Lipase
Cell Cycle Arrest
LIM Kinase
Glucokinase
HCAR
MNK
Complement System
Piezo Channel
Necroptosis
IDO
NR4A
E1/E2/E3 Enzyme
PROTAC Linker
ATP Citrate Lyase
Porcupine
EBI2/GPR183
Arginase
gp120/CD4
Photosensitizer
AIM2
MELK
Aromatase
IKZF
ASBT
Glutaminyl Cyclase
MIF
PAD
Thrombopoietin Receptor
Aminopeptidase
Urea Transporter
DAPK
p97
Kinesin
Taste receptor
TOPK
FLAP
Motilin Receptor
DNA Alkylation
Neprilysin
ATM/ATR
Adenosine Deaminase
Liposome
RAR/RXR
Neuropeptide W
Amylase
FABP
Huntingtin
Acetyl-CoA Carboxylase
FKBP
GPX
PKM
MicroRNA
Galectin
Haspin Kinase
Orphan Receptor
Protease
RANKL/RANK
Phosphorylase
Telomerase
GDNF
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
cGAS
Hippo pathway
Mdm2
GSNOR
ASCT
NAMPT
Carboxypeptidase
Gap Junction Protein
Lysosomal Autophagy
Sodium-dependent phosphate transporter
ADC Cytotoxin
IGF-2R

Keywords