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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes. Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases. TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

5-HT Receptor
Apoptosis
AChR
Autophagy
Adrenergic Receptor
Dopamine Receptor
Calcium Channel
Potassium Channel
EGFR
Histamine Receptor
Sodium Channel
GABA Receptor
Endogenous Metabolite
VEGFR
GluR
Histone Methyltransferase
TRP/TRPV Channel
GPCR
Prostaglandin Receptor
JAK
Cholinesterase (ChE)
p38 MAPK
Antibacterial
Src
Adenosine Receptor
FLT
Opioid Receptor
PKC
iGluR
PDGFR
Estrogen Receptor/ERR
Caspase
NF-κB
RAAS
FGFR
GSK-3
MMP
NO Synthase
CDK
Raf
TLR
c-Kit
c-Met/HGFR
Cannabinoid Receptor
ALK
ATPase
Bcr-Abl
HSP
Parasite
TNF
TGF-beta/Smad
Ras
COX
NMDAR
Estrogen/progestogen Receptor
PKA
Wnt/beta-catenin
Aurora Kinase
Cytochromes P450
ERK
CCR
Akt
P-gp
ROCK
Tyrosine Kinases
CXCR
Antibiotic
Casein Kinase
HIV Protease
S1P Receptor
Neurokinin receptor
Serotonin Transporter
Integrin
IGF-1R
P2X Receptor
c-RET
IL Receptor
LPL Receptor
Hedgehog/Smoothened
Reactive Oxygen Species
FAK
TAM Receptor
Norepinephrine
Sigma receptor
STAT
Trk receptor
PDE
Glucagon Receptor
HER
c-Fms
CFTR
Neuropeptide Y Receptor
PPAR
Proton pump
Syk
transporter
Antifungal
Chloride channel
Endothelin Receptor
Influenza Virus
Protease-activated Receptor
Cysteine Protease
PI3K
Cholecystokinin Receptor
cAMP
SARS-CoV
Ferroptosis
AMPK
Antioxidant
Drug Metabolite
DYRK
Leukotriene Receptor
Melanocortin Receptor
P2Y Receptor
SGLT
DNA/RNA Synthesis
LPA Receptor
NOS
OX Receptor
Bcl-2 Family
Bradykinin Receptor
Guanylate cyclase
JNK
Mitophagy
MRP
Vasopressin Receptor
Epigenetic Reader Domain
GNRH Receptor
Interleukin
Kras
BTK
MEK
Rho
ROS
Virus Protease
GTPase
ROS Kinase
S6 Kinase
ABC Transporter
Ephrin Receptor
GHSR
Lipoxygenase
mTOR
PARP
Beta Amyloid
CaMK
HCV Protease
MAPK
Phospholipase
Tyrosinase
CSF-1R
HDAC
HSV
Neurotensin Receptor
Smo
GPCR19
Monoamine Transporter
Somatostatin
Arrestin
CaSR
Discoidin Domain Receptor (DDR)
Serine/threonin kinase
Antiviral
GRK
MAO
Melatonin Receptor
PAFR
Topoisomerase
BCRP
Glucocorticoid Receptor
Immunology/Inflammation related
Mitochondrial Metabolism
Monocarboxylate transporter
OAT
Adenylyl Cyclase
Antifection
Bombesin Receptor
Carbonic Anhydrase
CGRP Receptor
CRFR
IκB/IKK
Microtubule Associated
Serine Protease
Apelin receptor
Dehydrogenase
Melanin-concentrating Hormone Receptor (MCHR)
Na+/Ca2+ Exchanger
Phosphatase
PYK2
Annexin A
Anti-infection
Chk
LTR
MT Receptor
Nrf2
OCT
Oxytocin Receptor
p53
Pim
Tie-2
TSH Receptor
BACE
CRM1
FXR
HBV
HCN Channel
HIF
HIF/HIF Prolyl-Hydroxylase
LDL
MLK
ACK1
AhR
Androgen Receptor
Aquaporin
Beta-Secretase
DNA
DNA Methyltransferase
FAAH
Monoamine Oxidase
Myosin
NOD
NPC1L1
Platelet aggregation
PLK
Progesterone Receptor
Proteasome
RIP kinase
Thrombin
Transferase
Acyltransferase
Adiponectin Receptor
Fatty Acid Synthase
Free radical scavengers
Glucosidase
Histone Demethylase
HMG-CoA Reductase
IAP
Imidazoline Receptor
IRAK
NADPH
PGE Synthase
Reductase
RSV
SGK
Sirtuin
CRISPR/Cas9
Glutathione Peroxidase
GST
Hck
Hydroxylase
Kisspeptin
MRGPR
MyD88
Na-K-Cl cotransporter
NOD-like Receptor (NLR)
Nucleoside Antimetabolite/Analog
PDK
Reverse Transcriptase
ribosome
ROR
Transaminase
VDAC
AAK1
Amino Acids and Derivatives
Amylin Receptor
Antifolate
Arginase
Aromatase
Aryl Hydrocarbon Receptor
Cell Cycle Arrest
c-Myc
DHFR
DNA gyrase
DNA-PK
DUB
E1/E2/E3 Enzyme
EBI2/GPR183
Gamma-secretase
GluCls
Glucokinase
Glutaminase
gp120/CD4
Histone Acetyltransferase
IFNAR
Indoleamine 2,3-Dioxygenase (IDO)
IRE1
LIM Kinase
LRRK2
MELK
MNK
Motilin Receptor
NADPH-oxidase
PAI-1
PAK
PERK
Piezo Channel
Porcupine
PTEN
Pyroptosis
Retinoid Receptor
RXFP receptor
Stearoyl-CoA Desaturase (SCD)
UGT
YAP
Adenosine Deaminase
AIM2
Aminopeptidase
Amylase
Angiotensin-converting Enzyme (ACE)
Anion Exchanger
ATM/ATR
ATP Citrate Lyase
Complement System
DAPK
DNA Alkylation
Dynamin
FLAP
Gap Junction Protein
Glutaminyl Cyclase
GlyT
GPX
GSNOR
Haspin Kinase
Hippo pathway
Huntingtin
Kinesin
Lipid
Liver X Receptor
Lysosomal Autophagy
Mdm2
MicroRNA
N-Acetylglucosaminyltransferase
NAMPT
Neprilysin
Neuropeptide W
p97
PAD
PD-1/PD-L1
Phosphorylase
PKM
PROTAC Linker
PROTACs
Protease
Survivin
Thrombopoietin Receptor
Thyroid hormone receptor(THR)
TOPK
Wee1
IGF-2R
Sodium-dependent phosphate transporter

Keywords