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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Calcium Channel
Dopamine Receptor
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
Antibacterial
GluR
TRP/TRPV Channel
p38 MAPK
Histone Methyltransferase
NF-κB
GPCR
iGluR
Cholinesterase (ChE)
Caspase
JAK
Prostaglandin Receptor
Src
Parasite
NO Synthase
Adenosine Receptor
FLT
ERK
Opioid Receptor
Akt
PKC
ROS
PDGFR
Estrogen Receptor/ERR
GSK-3
MMP
RAAS
TLR
FGFR
Raf
c-Met/HGFR
CDK
TNF
c-Kit
TGF-beta/Smad
COX
Bcr-Abl
HSP
Cannabinoid Receptor
ATPase
ALK
Wnt/beta-catenin
Cytochromes P450
PKA
P-gp
LPL Receptor
NMDAR
Reactive Oxygen Species
Estrogen/progestogen Receptor
Interleukin
Kras
HIV Protease
Antibiotic
Serotonin Transporter
Aurora Kinase
CCR
ROCK
Tyrosine Kinases
STAT
PI3K
CXCR
Integrin
IGF-1R
Drug Metabolite
Casein Kinase
Neurokinin receptor
S1P Receptor
Proton pump
P2X Receptor
Sigma receptor
Antifungal
DNA/RNA Synthesis
Trk receptor
c-RET
FAK
IL Receptor
Hedgehog/Smoothened
Influenza Virus
PPAR
PDE
SARS-CoV
TAM Receptor
JNK
Angiotensin-converting Enzyme (ACE)
Norepinephrine
c-Fms
Ferroptosis
CFTR
Virus Protease
Bcl-2 Family
HER
Chloride channel
mTOR
transporter
Syk
Cysteine Protease
AMPK
Protease-activated Receptor
Leukotriene Receptor
Endothelin Receptor
Beta Amyloid
Cholecystokinin Receptor
Glucagon Receptor
cAMP
P2Y Receptor
Mitophagy
PARP
Epigenetic Reader Domain
DYRK
SGLT
ROS Kinase
Antioxidant
Smo
OX Receptor
LPA Receptor
Melanocortin Receptor
MEK
MRP
Neuropeptide Y Receptor
Anti-infection
S6 Kinase
NOS
Guanylate cyclase
Vasopressin Receptor
Lipoxygenase
BTK
Bradykinin Receptor
GNRH Receptor
HSV
CaMK
Tyrosinase
GTPase
Rho
ABC Transporter
Mitochondrial Metabolism
GPCR19
Ephrin Receptor
Phospholipase
HCV Protease
PERK
MAPK
HDAC
Arrestin
Monoamine Transporter
Phosphatase
CaSR
Serine Protease
Serine/threonin kinase
Neurotensin Receptor
CSF-1R
BCRP
Nrf2
HIF/HIF Prolyl-Hydroxylase
Monoamine Oxidase
Monocarboxylate transporter
Dehydrogenase
Immunology/Inflammation related
PAFR
Somatostatin
GHSR
Discoidin Domain Receptor (DDR)
Microtubule Associated
Melatonin Receptor
MAO
GRK
Antifection
PGE Synthase
Antiviral
IκB/IKK
Na+/Ca2+ Exchanger
Tie-2
Glucocorticoid Receptor
Bombesin Receptor
OAT
MDM-2/p53
Apelin receptor
Carbonic Anhydrase
OCT
HBV
FXR
PYK2
Topoisomerase
Sirtuin
Adenylyl Cyclase
Nucleoside Antimetabolite/Analog
RIP kinase
Glucosidase
Beta-Secretase
CRFR
Oxytocin Receptor
CGRP Receptor
NOD-like Receptor (NLR)
MLK
Melanin-concentrating Hormone Receptor (MCHR)
CRM1
LTR
Pim
Annexin A
Neuropeptide FF Receptor
MT Receptor
Chk
TSH Receptor
Hydroxylase
Transferase
Reductase
BACE
Histone Demethylase
Progesterone Receptor
Glutaminase
Aryl Hydrocarbon Receptor
Myosin
LDL
HCN Channel
Fatty Acid Synthase
Androgen Receptor
Acyltransferase
RSV
Aquaporin
HIF
DNA Methyltransferase
IRAK
HMG-CoA Reductase
Thrombin
p53
Proteasome
PROTACs
NPC1L1
MyD88
IFNAR
NADPH
Glutathione Peroxidase
c-Myc
Gamma-secretase
FAAH
PTEN
glycosidase
DNA
FOXO
PLK
Platelet aggregation
NOD
AhR
Imidazoline Receptor
Thyroid hormone receptor(THR)
Amino Acids and Derivatives
VDAC
Hck
IAP
Adiponectin Receptor
PAK
Stearoyl-CoA Desaturase (SCD)
ACK1
OXPHOS
Survivin
Free radical scavengers
Histone Acetyltransferase
Pyroptosis
GST
Reverse Transcriptase
PDK
SGK
Transaminase
ROR
Dynamin
YAP
Succinate Receptor 1 (SUCNR1)
Kisspeptin
Liver X Receptor
UGT
Na-K-Cl cotransporter
Cadherin
DUB
Lipid
MRGPR
LRRK2
PAI-1
ribosome
CRISPR/Cas9
PD-1/PD-L1
DHFR
Piezo Channel
DNA-PK
EBI2/GPR183
Arginase
Lipase
Necroptosis
gp120/CD4
AAK1
Photosensitizer
Antifolate
Cell Cycle Arrest
LIM Kinase
Glucokinase
NR4A
IDO
IRE1
E1/E2/E3 Enzyme
PACAP
DNA gyrase
GlyT
PROTAC Linker
HCAR
Indoleamine 2,3-Dioxygenase (IDO)
ATP Citrate Lyase
Wee1
MNK
Porcupine
STING
AIM2
GluCls
MELK
Retinoid Receptor
Aromatase
RXFP receptor
Cuproptosis
Complement System
NADPH-oxidase
IKZF
Mdm2
Taste receptor
MicroRNA
GSNOR
RAR/RXR
GDNF
ASBT
Glutaminyl Cyclase
Neuropeptide W
MIF
TOPK
Galectin
N-Acetylglucosaminyltransferase
ASCT
ATG
NAMPT
RANKL/RANK
Amylase
FLAP
Motilin Receptor
FABP
Haspin Kinase
Phosphorylase
Anion Exchanger
Molecular Glues
DNA Alkylation
PAD
Thrombopoietin Receptor
Orphan Receptor
Telomerase
Huntingtin
Aminopeptidase
Urea Transporter
cGAS
Neprilysin
Hippo pathway
ATM/ATR
Acetyl-CoA Carboxylase
Carboxypeptidase
FKBP
GPX
Protease
Adenosine Deaminase
Gap Junction Protein
DAPK
Lysosomal Autophagy
p97
Liposome
Kinesin
PKM
ADC Cytotoxin
Sodium-dependent phosphate transporter
IGF-2R

Keywords