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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Dopamine Receptor
Calcium Channel
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
Antibacterial
GluR
TRP/TRPV Channel
Histone Methyltransferase
GPCR
p38 MAPK
Cholinesterase (ChE)
Prostaglandin Receptor
iGluR
JAK
Caspase
Src
Adenosine Receptor
FLT
Parasite
PKC
Opioid Receptor
NF-κB
PDGFR
Estrogen Receptor/ERR
GSK-3
FGFR
MMP
NO Synthase
RAAS
c-Met/HGFR
Raf
CDK
c-Kit
TNF
TLR
TGF-beta/Smad
ERK
HSP
Bcr-Abl
Cannabinoid Receptor
ATPase
Akt
ALK
COX
Cytochromes P450
Wnt/beta-catenin
LPL Receptor
NMDAR
PKA
Estrogen/progestogen Receptor
Reactive Oxygen Species
Kras
Aurora Kinase
Serotonin Transporter
Antibiotic
ROCK
HIV Protease
P-gp
CCR
Tyrosine Kinases
CXCR
Neurokinin receptor
Casein Kinase
S1P Receptor
IGF-1R
Integrin
P2X Receptor
Proton pump
Sigma receptor
STAT
c-RET
IL Receptor
FAK
Trk receptor
Hedgehog/Smoothened
Interleukin
Drug Metabolite
PI3K
TAM Receptor
Antifungal
c-Fms
PDE
Norepinephrine
SARS-CoV
Influenza Virus
PPAR
Virus Protease
Angiotensin-converting Enzyme (ACE)
CFTR
HER
Chloride channel
transporter
Syk
Bcl-2 Family
Endothelin Receptor
Protease-activated Receptor
Cysteine Protease
Ferroptosis
DNA/RNA Synthesis
Leukotriene Receptor
Cholecystokinin Receptor
Glucagon Receptor
cAMP
P2Y Receptor
Mitophagy
AMPK
DYRK
SGLT
JNK
Epigenetic Reader Domain
mTOR
ROS Kinase
Anti-infection
Smo
OX Receptor
Antioxidant
PARP
Neuropeptide Y Receptor
Beta Amyloid
LPA Receptor
NOS
Melanocortin Receptor
MEK
S6 Kinase
MRP
Guanylate cyclase
Vasopressin Receptor
BTK
Bradykinin Receptor
GNRH Receptor
Lipoxygenase
ROS
Phospholipase
ABC Transporter
GTPase
Rho
CaMK
HCV Protease
Tyrosinase
HSV
Ephrin Receptor
MAPK
GPCR19
Arrestin
Monoamine Transporter
HDAC
Monoamine Oxidase
CSF-1R
Neurotensin Receptor
CaSR
Serine Protease
Mitochondrial Metabolism
Somatostatin
Discoidin Domain Receptor (DDR)
Serine/threonin kinase
GHSR
PAFR
BCRP
Monocarboxylate transporter
Phosphatase
GRK
Antiviral
Immunology/Inflammation related
IκB/IKK
Antifection
PGE Synthase
Microtubule Associated
Melatonin Receptor
MAO
Dehydrogenase
Glucocorticoid Receptor
Bombesin Receptor
OAT
Tie-2
Topoisomerase
Na+/Ca2+ Exchanger
OCT
Apelin receptor
HIF/HIF Prolyl-Hydroxylase
PYK2
Carbonic Anhydrase
Oxytocin Receptor
MDM-2/p53
Glucosidase
Beta-Secretase
Adenylyl Cyclase
FXR
Nrf2
CRFR
Pim
Annexin A
MT Receptor
Chk
Melanin-concentrating Hormone Receptor (MCHR)
Neuropeptide FF Receptor
CRM1
CGRP Receptor
p53
LTR
HBV
Nucleoside Antimetabolite/Analog
TSH Receptor
Hydroxylase
Transferase
BACE
DNA Methyltransferase
Thrombin
Myosin
Acyltransferase
Glutaminase
LDL
MLK
Sirtuin
Progesterone Receptor
HCN Channel
HIF
AhR
NOD-like Receptor (NLR)
Gamma-secretase
RSV
PLK
Proteasome
NPC1L1
Reductase
RIP kinase
Fatty Acid Synthase
Androgen Receptor
Aquaporin
Aryl Hydrocarbon Receptor
Histone Demethylase
PERK
FAAH
DNA
Imidazoline Receptor
Platelet aggregation
NOD
IFNAR
NADPH
Stearoyl-CoA Desaturase (SCD)
ACK1
SGK
Thyroid hormone receptor(THR)
HMG-CoA Reductase
MyD88
PTEN
Free radical scavengers
Pyroptosis
VDAC
IAP
Adiponectin Receptor
PAK
Histone Acetyltransferase
GST
Reverse Transcriptase
IRAK
Hck
Na-K-Cl cotransporter
PDK
ROR
Succinate Receptor 1 (SUCNR1)
Kisspeptin
Transaminase
UGT
Glutathione Peroxidase
OXPHOS
MRGPR
LRRK2
ribosome
CRISPR/Cas9
c-Myc
Piezo Channel
YAP
IDO
Lipid
Amino Acids and Derivatives
Cell Cycle Arrest
LIM Kinase
Glucokinase
DUB
MNK
Complement System
DHFR
DNA-PK
AAK1
Antifolate
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
Survivin
Cuproptosis
IRE1
PACAP
DNA gyrase
GluCls
Retinoid Receptor
RXFP receptor
NADPH-oxidase
NR4A
E1/E2/E3 Enzyme
PROTAC Linker
ATP Citrate Lyase
Porcupine
EBI2/GPR183
Arginase
gp120/CD4
Photosensitizer
Liver X Receptor
AIM2
PAI-1
MELK
Aromatase
PD-1/PD-L1
IKZF
Phosphorylase
Molecular Glues
Telomerase
MicroRNA
Dynamin
Galectin
Haspin Kinase
Protease
TOPK
FLAP
Motilin Receptor
DNA Alkylation
Neprilysin
ATM/ATR
FOXO
Adenosine Deaminase
ASBT
Glutaminyl Cyclase
MIF
GlyT
PAD
Thrombopoietin Receptor
Aminopeptidase
Urea Transporter
DAPK
p97
Kinesin
RAR/RXR
Neuropeptide W
Amylase
Cadherin
Huntingtin
FKBP
GPX
PKM
PROTACs
GDNF
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
cGAS
Hippo pathway
Mdm2
GSNOR
ASCT
NAMPT
Gap Junction Protein
Lysosomal Autophagy
ADC Cytotoxin
Sodium-dependent phosphate transporter
IGF-2R

Keywords