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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Dopamine Receptor
Calcium Channel
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
GluR
Antibacterial
TRP/TRPV Channel
Histone Methyltransferase
GPCR
p38 MAPK
iGluR
Cholinesterase (ChE)
Prostaglandin Receptor
JAK
Caspase
Src
Adenosine Receptor
PKC
FLT
Parasite
NF-κB
Opioid Receptor
PDGFR
Estrogen Receptor/ERR
GSK-3
NO Synthase
FGFR
MMP
RAAS
c-Met/HGFR
Raf
CDK
c-Kit
TLR
Akt
TNF
ERK
TGF-beta/Smad
ATPase
Bcr-Abl
Cannabinoid Receptor
HSP
ALK
COX
Cytochromes P450
PKA
Wnt/beta-catenin
LPL Receptor
NMDAR
Reactive Oxygen Species
Estrogen/progestogen Receptor
Kras
Aurora Kinase
Antibiotic
HIV Protease
Serotonin Transporter
ROCK
CCR
P-gp
Tyrosine Kinases
CXCR
Neurokinin receptor
IGF-1R
Casein Kinase
Integrin
S1P Receptor
P2X Receptor
STAT
Proton pump
Sigma receptor
Interleukin
PI3K
c-RET
IL Receptor
FAK
Drug Metabolite
Hedgehog/Smoothened
Trk receptor
TAM Receptor
Antifungal
PPAR
PDE
Norepinephrine
c-Fms
SARS-CoV
Influenza Virus
Virus Protease
Angiotensin-converting Enzyme (ACE)
CFTR
HER
Chloride channel
Bcl-2 Family
transporter
Syk
Ferroptosis
Cysteine Protease
DNA/RNA Synthesis
Protease-activated Receptor
Leukotriene Receptor
Endothelin Receptor
Cholecystokinin Receptor
JNK
cAMP
Epigenetic Reader Domain
AMPK
P2Y Receptor
Mitophagy
PARP
Glucagon Receptor
mTOR
DYRK
ROS Kinase
Antioxidant
Smo
OX Receptor
SGLT
Melanocortin Receptor
Anti-infection
Neuropeptide Y Receptor
Beta Amyloid
LPA Receptor
S6 Kinase
NOS
MRP
Guanylate cyclase
Vasopressin Receptor
MEK
BTK
GNRH Receptor
Bradykinin Receptor
Lipoxygenase
Tyrosinase
GTPase
Rho
ABC Transporter
ROS
GPCR19
Ephrin Receptor
Phospholipase
HCV Protease
HSV
CaMK
MAPK
HDAC
Arrestin
Monoamine Transporter
CaSR
Neurotensin Receptor
CSF-1R
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
Monoamine Oxidase
Monocarboxylate transporter
Serine Protease
Serine/threonin kinase
Somatostatin
GHSR
Discoidin Domain Receptor (DDR)
Phosphatase
PAFR
BCRP
Melatonin Receptor
MAO
Immunology/Inflammation related
GRK
Antifection
PGE Synthase
Antiviral
IκB/IKK
Microtubule Associated
Dehydrogenase
Na+/Ca2+ Exchanger
Tie-2
Glucocorticoid Receptor
Topoisomerase
Bombesin Receptor
OAT
Apelin receptor
Carbonic Anhydrase
OCT
PYK2
MDM-2/p53
Adenylyl Cyclase
FXR
Glucosidase
Beta-Secretase
Sirtuin
Nrf2
CRFR
Oxytocin Receptor
Melanin-concentrating Hormone Receptor (MCHR)
CRM1
LTR
HBV
Pim
Nucleoside Antimetabolite/Analog
Annexin A
Neuropeptide FF Receptor
MT Receptor
Chk
TSH Receptor
Hydroxylase
CGRP Receptor
p53
Transferase
BACE
Histone Demethylase
PERK
Progesterone Receptor
Glutaminase
Myosin
LDL
HCN Channel
Acyltransferase
HIF
DNA Methyltransferase
Thrombin
MLK
Proteasome
NPC1L1
Reductase
Aryl Hydrocarbon Receptor
IAP
RIP kinase
Gamma-secretase
Fatty Acid Synthase
FAAH
DNA
Androgen Receptor
RSV
Aquaporin
PLK
Platelet aggregation
NOD
AhR
NOD-like Receptor (NLR)
Imidazoline Receptor
Thyroid hormone receptor(THR)
MyD88
IFNAR
NADPH
VDAC
Adiponectin Receptor
PAK
Stearoyl-CoA Desaturase (SCD)
ACK1
PTEN
Free radical scavengers
Histone Acetyltransferase
Pyroptosis
GST
Reverse Transcriptase
SGK
IRAK
HMG-CoA Reductase
Transaminase
ROR
Succinate Receptor 1 (SUCNR1)
Glutathione Peroxidase
c-Myc
Kisspeptin
Hck
UGT
Na-K-Cl cotransporter
OXPHOS
Survivin
MRGPR
LRRK2
ribosome
CRISPR/Cas9
PDK
DHFR
Piezo Channel
DNA-PK
EBI2/GPR183
Amino Acids and Derivatives
YAP
Arginase
gp120/CD4
AAK1
Photosensitizer
Antifolate
Cell Cycle Arrest
Liver X Receptor
LIM Kinase
Glucokinase
NR4A
IDO
IRE1
E1/E2/E3 Enzyme
PACAP
DNA gyrase
PROTAC Linker
DUB
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
ATP Citrate Lyase
Lipid
MNK
Porcupine
AIM2
GluCls
PAI-1
MELK
Retinoid Receptor
Aromatase
FOXO
RXFP receptor
Cuproptosis
Complement System
NADPH-oxidase
PD-1/PD-L1
IKZF
Mdm2
PROTACs
MicroRNA
GSNOR
RAR/RXR
GDNF
ASBT
Dynamin
Glutaminyl Cyclase
Neuropeptide W
MIF
TOPK
Galectin
N-Acetylglucosaminyltransferase
ASCT
ATG
NAMPT
Amylase
FLAP
Motilin Receptor
Haspin Kinase
Phosphorylase
GlyT
Anion Exchanger
Molecular Glues
DNA Alkylation
PAD
Cadherin
Thrombopoietin Receptor
Telomerase
Huntingtin
Aminopeptidase
Urea Transporter
cGAS
Neprilysin
Hippo pathway
ATM/ATR
FKBP
GPX
Protease
Adenosine Deaminase
Gap Junction Protein
DAPK
p97
Lysosomal Autophagy
Kinesin
PKM
ADC Cytotoxin
Sodium-dependent phosphate transporter
IGF-2R

Keywords