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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Calcium Channel
Dopamine Receptor
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
Antibacterial
GluR
TRP/TRPV Channel
p38 MAPK
Histone Methyltransferase
NF-κB
GPCR
iGluR
Cholinesterase (ChE)
Caspase
Prostaglandin Receptor
JAK
Src
Parasite
NO Synthase
Adenosine Receptor
FLT
Opioid Receptor
ERK
Akt
ROS
PKC
PDGFR
Estrogen Receptor/ERR
GSK-3
MMP
TLR
RAAS
FGFR
Raf
c-Met/HGFR
TNF
CDK
c-Kit
TGF-beta/Smad
COX
Cannabinoid Receptor
HSP
ATPase
Bcr-Abl
ALK
Wnt/beta-catenin
Cytochromes P450
PKA
P-gp
LPL Receptor
NMDAR
Reactive Oxygen Species
Estrogen/progestogen Receptor
Interleukin
Kras
Antibiotic
Aurora Kinase
HIV Protease
Serotonin Transporter
CCR
ROCK
Tyrosine Kinases
STAT
PI3K
CXCR
IGF-1R
Integrin
Neurokinin receptor
Casein Kinase
Drug Metabolite
S1P Receptor
Proton pump
Sigma receptor
P2X Receptor
Antifungal
Trk receptor
DNA/RNA Synthesis
FAK
c-RET
IL Receptor
Influenza Virus
Hedgehog/Smoothened
PPAR
PDE
JNK
SARS-CoV
TAM Receptor
Angiotensin-converting Enzyme (ACE)
c-Fms
Norepinephrine
Ferroptosis
CFTR
Virus Protease
Bcl-2 Family
HER
Chloride channel
transporter
Syk
mTOR
Cysteine Protease
Protease-activated Receptor
AMPK
Leukotriene Receptor
Endothelin Receptor
Beta Amyloid
Cholecystokinin Receptor
Glucagon Receptor
cAMP
P2Y Receptor
PARP
Mitophagy
Epigenetic Reader Domain
DYRK
ROS Kinase
SGLT
Antioxidant
Melanocortin Receptor
OX Receptor
Smo
LPA Receptor
MEK
MRP
Neuropeptide Y Receptor
S6 Kinase
NOS
Guanylate cyclase
Vasopressin Receptor
Lipoxygenase
Anti-infection
BTK
Bradykinin Receptor
GNRH Receptor
HSV
CaMK
Mitochondrial Metabolism
GPCR19
Tyrosinase
ABC Transporter
GTPase
Rho
Ephrin Receptor
Phospholipase
MAPK
HCV Protease
PERK
HDAC
Arrestin
Monoamine Transporter
Serine Protease
HIF/HIF Prolyl-Hydroxylase
Phosphatase
Serine/threonin kinase
Nrf2
CaSR
Neurotensin Receptor
BCRP
CSF-1R
Monoamine Oxidase
Immunology/Inflammation related
PAFR
Monocarboxylate transporter
GHSR
Somatostatin
Discoidin Domain Receptor (DDR)
Microtubule Associated
Dehydrogenase
Melatonin Receptor
MAO
Antifection
PGE Synthase
IκB/IKK
GRK
Antiviral
OAT
Na+/Ca2+ Exchanger
MDM-2/p53
Tie-2
Glucocorticoid Receptor
Bombesin Receptor
Apelin receptor
FXR
Topoisomerase
Carbonic Anhydrase
HBV
Sirtuin
PYK2
OCT
CGRP Receptor
MLK
Nucleoside Antimetabolite/Analog
CRFR
Oxytocin Receptor
Adenylyl Cyclase
RIP kinase
Glucosidase
Beta-Secretase
NOD-like Receptor (NLR)
Chk
LTR
TSH Receptor
Hydroxylase
CRM1
Melanin-concentrating Hormone Receptor (MCHR)
Neuropeptide FF Receptor
Pim
Annexin A
MT Receptor
RSV
Aryl Hydrocarbon Receptor
LDL
p53
Histone Demethylase
Progesterone Receptor
HCN Channel
HIF
IRAK
Glutaminase
Fatty Acid Synthase
Androgen Receptor
Aquaporin
HMG-CoA Reductase
Reductase
Myosin
Acyltransferase
Transferase
BACE
DNA Methyltransferase
Thrombin
Gamma-secretase
PLK
MyD88
Glutathione Peroxidase
PTEN
PROTACs
FAAH
glycosidase
DNA
Imidazoline Receptor
c-Myc
Platelet aggregation
NOD
Proteasome
NPC1L1
FOXO
IFNAR
NADPH
AhR
Amino Acids and Derivatives
OXPHOS
Free radical scavengers
Pyroptosis
VDAC
IAP
Adiponectin Receptor
PAK
Histone Acetyltransferase
GST
Reverse Transcriptase
Survivin
Thyroid hormone receptor(THR)
Stearoyl-CoA Desaturase (SCD)
ACK1
PDK
SGK
ROR
Dynamin
DUB
Cadherin
MRGPR
LRRK2
ribosome
CRISPR/Cas9
Liver X Receptor
PAI-1
PD-1/PD-L1
Transaminase
UGT
Succinate Receptor 1 (SUCNR1)
Kisspeptin
YAP
Hck
Na-K-Cl cotransporter
Lipid
Lipase
Cell Cycle Arrest
LIM Kinase
Glucokinase
HCAR
MNK
Complement System
IRE1
PACAP
DNA gyrase
STING
GluCls
Retinoid Receptor
RXFP receptor
NADPH-oxidase
NR4A
E1/E2/E3 Enzyme
PROTAC Linker
ATP Citrate Lyase
Porcupine
EBI2/GPR183
Arginase
gp120/CD4
Photosensitizer
AIM2
MELK
Aromatase
Antifolate
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
Cuproptosis
DHFR
DNA-PK
AAK1
Piezo Channel
Necroptosis
IDO
IKZF
MicroRNA
Galectin
Haspin Kinase
Orphan Receptor
Protease
RAR/RXR
Neuropeptide W
Amylase
FABP
Huntingtin
Acetyl-CoA Carboxylase
FKBP
GPX
PKM
GDNF
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
cGAS
Hippo pathway
Mdm2
GSNOR
ASCT
NAMPT
Carboxypeptidase
Gap Junction Protein
Lysosomal Autophagy
ASBT
Glutaminyl Cyclase
MIF
PAD
Thrombopoietin Receptor
Aminopeptidase
Urea Transporter
DAPK
p97
Kinesin
Taste receptor
TOPK
FLAP
Motilin Receptor
DNA Alkylation
Neprilysin
ATM/ATR
Adenosine Deaminase
Liposome
RANKL/RANK
Phosphorylase
Molecular Glues
Telomerase
Sodium-dependent phosphate transporter
IGF-2R
ADC Cytotoxin

Keywords