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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes.

Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases.

TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
5-HT Receptor
Autophagy
AChR
Adrenergic Receptor
Calcium Channel
Dopamine Receptor
Potassium Channel
Endogenous Metabolite
EGFR
Histamine Receptor
Ras
Sodium Channel
GABA Receptor
VEGFR
Antibacterial
GluR
TRP/TRPV Channel
p38 MAPK
Histone Methyltransferase
NF-κB
GPCR
iGluR
Cholinesterase (ChE)
Caspase
Prostaglandin Receptor
JAK
Src
Parasite
NO Synthase
Adenosine Receptor
FLT
Opioid Receptor
Akt
ERK
ROS
PKC
PDGFR
Estrogen Receptor/ERR
MMP
GSK-3
TLR
RAAS
FGFR
Raf
CDK
c-Met/HGFR
TNF
c-Kit
TGF-beta/Smad
COX
Cannabinoid Receptor
HSP
Bcr-Abl
ATPase
ALK
Wnt/beta-catenin
Cytochromes P450
P-gp
PKA
LPL Receptor
NMDAR
Reactive Oxygen Species
Estrogen/progestogen Receptor
Interleukin
Kras
HIV Protease
Antibiotic
Aurora Kinase
Serotonin Transporter
CCR
ROCK
Tyrosine Kinases
STAT
PI3K
CXCR
Integrin
Neurokinin receptor
IGF-1R
Drug Metabolite
Casein Kinase
S1P Receptor
Proton pump
P2X Receptor
Sigma receptor
Antifungal
DNA/RNA Synthesis
FAK
Trk receptor
c-RET
IL Receptor
Influenza Virus
Hedgehog/Smoothened
PDE
PPAR
SARS-CoV
TAM Receptor
Norepinephrine
Angiotensin-converting Enzyme (ACE)
c-Fms
JNK
Ferroptosis
CFTR
Bcl-2 Family
Virus Protease
HER
Chloride channel
transporter
Syk
mTOR
Cysteine Protease
Protease-activated Receptor
AMPK
Leukotriene Receptor
Endothelin Receptor
Beta Amyloid
Cholecystokinin Receptor
Glucagon Receptor
cAMP
P2Y Receptor
Mitophagy
Epigenetic Reader Domain
PARP
DYRK
ROS Kinase
SGLT
OX Receptor
Smo
Melanocortin Receptor
Antioxidant
LPA Receptor
MEK
MRP
Neuropeptide Y Receptor
Anti-infection
S6 Kinase
NOS
Guanylate cyclase
Vasopressin Receptor
Lipoxygenase
BTK
Bradykinin Receptor
Tyrosinase
GNRH Receptor
HSV
CaMK
Mitochondrial Metabolism
GPCR19
Phospholipase
GTPase
Rho
Ephrin Receptor
ABC Transporter
HCV Protease
MAPK
PERK
HDAC
Arrestin
Monoamine Transporter
Phosphatase
Serine/threonin kinase
Nrf2
Neurotensin Receptor
BCRP
Serine Protease
HIF/HIF Prolyl-Hydroxylase
CSF-1R
CaSR
Monoamine Oxidase
Monocarboxylate transporter
Somatostatin
Discoidin Domain Receptor (DDR)
Microtubule Associated
Immunology/Inflammation related
PAFR
GHSR
Dehydrogenase
Melatonin Receptor
Antifection
PGE Synthase
IκB/IKK
MAO
GRK
Antiviral
OAT
Tie-2
Na+/Ca2+ Exchanger
MDM-2/p53
Glucocorticoid Receptor
Bombesin Receptor
FXR
Topoisomerase
PYK2
Apelin receptor
Carbonic Anhydrase
HBV
Sirtuin
OCT
CGRP Receptor
MLK
Adenylyl Cyclase
RIP kinase
Glucosidase
Beta-Secretase
CRFR
Oxytocin Receptor
Nucleoside Antimetabolite/Analog
NOD-like Receptor (NLR)
CRM1
Chk
Melanin-concentrating Hormone Receptor (MCHR)
Neuropeptide FF Receptor
LTR
TSH Receptor
Hydroxylase
Pim
Annexin A
MT Receptor
Aryl Hydrocarbon Receptor
LDL
p53
Glutaminase
Fatty Acid Synthase
Androgen Receptor
Aquaporin
HMG-CoA Reductase
RSV
Reductase
Myosin
Acyltransferase
Progesterone Receptor
HCN Channel
HIF
IRAK
Histone Demethylase
Transferase
BACE
DNA Methyltransferase
Thrombin
MyD88
Glutathione Peroxidase
PTEN
Gamma-secretase
PLK
Proteasome
NPC1L1
FOXO
c-Myc
Platelet aggregation
NOD
PROTACs
FAAH
glycosidase
DNA
Imidazoline Receptor
IFNAR
NADPH
AhR
OXPHOS
Free radical scavengers
Pyroptosis
Survivin
Amino Acids and Derivatives
Thyroid hormone receptor(THR)
PAK
Histone Acetyltransferase
GST
Reverse Transcriptase
VDAC
IAP
Adiponectin Receptor
Stearoyl-CoA Desaturase (SCD)
ACK1
PDK
SGK
Cadherin
MRGPR
LRRK2
Transaminase
UGT
ROR
Dynamin
DUB
Succinate Receptor 1 (SUCNR1)
Kisspeptin
Liver X Receptor
PAI-1
PD-1/PD-L1
ribosome
CRISPR/Cas9
YAP
Hck
Na-K-Cl cotransporter
Lipid
IRE1
PACAP
DNA gyrase
STING
GluCls
Retinoid Receptor
RXFP receptor
NADPH-oxidase
Antifolate
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
Wee1
Cuproptosis
Lipase
Cell Cycle Arrest
LIM Kinase
Glucokinase
HCAR
MNK
Complement System
DHFR
DNA-PK
AAK1
EBI2/GPR183
Arginase
gp120/CD4
Photosensitizer
AIM2
MELK
Aromatase
NR4A
E1/E2/E3 Enzyme
PROTAC Linker
ATP Citrate Lyase
Porcupine
Piezo Channel
Necroptosis
IDO
IKZF
RAR/RXR
Neuropeptide W
Amylase
FABP
Huntingtin
Acetyl-CoA Carboxylase
FKBP
GPX
PKM
ASBT
Glutaminyl Cyclase
MIF
PAD
Thrombopoietin Receptor
Aminopeptidase
Urea Transporter
DAPK
p97
Kinesin
MicroRNA
Galectin
Haspin Kinase
Orphan Receptor
Protease
Taste receptor
TOPK
FLAP
Motilin Receptor
DNA Alkylation
Neprilysin
ATM/ATR
Adenosine Deaminase
Liposome
Mdm2
GSNOR
ASCT
NAMPT
Carboxypeptidase
Gap Junction Protein
Lysosomal Autophagy
GDNF
N-Acetylglucosaminyltransferase
ATG
Anion Exchanger
cGAS
Hippo pathway
RANKL/RANK
Phosphorylase
Molecular Glues
Telomerase
Sodium-dependent phosphate transporter
IGF-2R
ADC Cytotoxin

Keywords